Identification of potential models for predicting progestin insensitivity in patients with endometrial atypical hyperplasia and endometrioid endometrial cancer based on ATAC-Seq and RNA-Seq integrated analysis

Identification of potential models for predicting progestin insensitivity in patients with endometrial atypical hyperplasia and endometrioid endometrial cancer based on ATAC-Seq and RNA-Seq integrated analysis

Objective: The aim of this study was to establish predictive models based on the molecular profiles of endometrial lesions, which might help identify progestin-insensitive endometrial atypical hyperplasia (EAH) or endometrioid endometrial cancer (EEC) patients before progestin-based fertility-preser...

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Bibliographic Details
Main Authors: Jia-Li Hu, Gulinazi Yierfulati, Lu-Lu Wang, Bing-Yi Yang, Qiao-Ying Lv, Xiao-Jun Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Genetics
Subjects:
predictive models
progestin insensitivity
endometrial atypical hyperplasia
endometrioid endometrial cancer
ATAC-seq
RNA-seq
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.952083/full

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https://www.frontiersin.org/articles/10.3389/fgene.2022.952083/full

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