Comparison of two sedation protocols for diagnostic radiography in dogs with hip dysplasia
Hip dysplasia is an alteration with a high incidence in large dogs. The aim of the study was to compare the association of xylazine or dexmedetomidine with fentanyl for radiography with joint distractor for the diagnosis of hip dysplasia. Fifteen healthy dogs, German Shepherd and Belgian Shepherd, w...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-06-01
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| Series: | Veterinary and Animal Science |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2451943X2300011X |
| _version_ | 1827940542718148608 |
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| author | Suzane Lilian Beier Marcos Paulo Antunes de Lima Felipe Gaia de Sousa Renata Andrade Silva Natália Fagundes Milena Fascina Bovi Renato Cesar Sacchetto Tôrres |
| author_facet | Suzane Lilian Beier Marcos Paulo Antunes de Lima Felipe Gaia de Sousa Renata Andrade Silva Natália Fagundes Milena Fascina Bovi Renato Cesar Sacchetto Tôrres |
| author_sort | Suzane Lilian Beier |
| collection | DOAJ |
| description | Hip dysplasia is an alteration with a high incidence in large dogs. The aim of the study was to compare the association of xylazine or dexmedetomidine with fentanyl for radiography with joint distractor for the diagnosis of hip dysplasia. Fifteen healthy dogs, German Shepherd and Belgian Shepherd, were randomly submitted to treatments 0.2 mg/kg xylazine + 2.5 µg/kg fentanyl (XF) or 2 µg/kg dexmedetomidine + 2.5 µg/kg fentanyl (DF), intravenously. HR, f, SAP, MAP, DAP and TR were evaluated at intervals of 5 min before and after the administration of treatments; pH, PaCO2, PaO2, BE, HCO3−, SaO2, Na+, K+ and Hb at 5 and 15 min after treatment administration; and the quality of sedation at intervals of 5 min after administration of treatments. Latency, duration, and recovery times were also compared. The HR values showed a significant reduction in both groups, as well as pH, PaCO2, PaO2 and SaO2. Latency, duration and recovery times, and quality of sedation did not differ statistically between groups. Xylazine and fentanyl or dexmedetomidine and fentanyl combinations provide adequate sedation and analgesia for performing diagnostic radiographic procedures for hip dysplasia. However, oxygen supplementation is recommended to increase protocol safety. |
| first_indexed | 2024-03-13T09:10:53Z |
| format | Article |
| id | doaj.art-4c2c5c923ea94f9fb7e29e8ff19dbe21 |
| institution | Directory Open Access Journal |
| issn | 2451-943X |
| language | English |
| last_indexed | 2024-03-13T09:10:53Z |
| publishDate | 2023-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Veterinary and Animal Science |
| spelling | doaj.art-4c2c5c923ea94f9fb7e29e8ff19dbe212023-05-27T04:26:17ZengElsevierVeterinary and Animal Science2451-943X2023-06-0120100294Comparison of two sedation protocols for diagnostic radiography in dogs with hip dysplasiaSuzane Lilian Beier0Marcos Paulo Antunes de Lima1Felipe Gaia de Sousa2Renata Andrade Silva3Natália Fagundes4Milena Fascina Bovi5Renato Cesar Sacchetto Tôrres6Department of Veterinary Clinic and Surgery, School of Veterinary Medicine, Federal University of Minas Gerais, 6627 Antônio Carlos Av, Pampulha, Belo Horizonte 31270-901, Minas Gerais, BrazilDepartment of Veterinary Clinic and Surgery, School of Veterinary Medicine, Federal University of Minas Gerais, 6627 Antônio Carlos Av, Pampulha, Belo Horizonte 31270-901, Minas Gerais, BrazilCorresponding author at: Department of Veterinary Clinic and Surgery, Veterinary School, Federal University of Minas Gerais 6627 Antônio Carlos Av, Pampulha, Belo Horizonte 31270-901, Minas Gerais, Brazil.; Department of Veterinary Clinic and Surgery, School of Veterinary Medicine, Federal University of Minas Gerais, 6627 Antônio Carlos Av, Pampulha, Belo Horizonte 31270-901, Minas Gerais, BrazilDepartment of Veterinary Clinic and Surgery, School of Veterinary Medicine, Federal University of Minas Gerais, 6627 Antônio Carlos Av, Pampulha, Belo Horizonte 31270-901, Minas Gerais, BrazilDepartment of Veterinary Clinic and Surgery, School of Veterinary Medicine, Federal University of Minas Gerais, 6627 Antônio Carlos Av, Pampulha, Belo Horizonte 31270-901, Minas Gerais, BrazilDepartment of Veterinary Clinic and Surgery, School of Veterinary Medicine, Federal University of Minas Gerais, 6627 Antônio Carlos Av, Pampulha, Belo Horizonte 31270-901, Minas Gerais, BrazilDepartment of Veterinary Clinic and Surgery, School of Veterinary Medicine, Federal University of Minas Gerais, 6627 Antônio Carlos Av, Pampulha, Belo Horizonte 31270-901, Minas Gerais, BrazilHip dysplasia is an alteration with a high incidence in large dogs. The aim of the study was to compare the association of xylazine or dexmedetomidine with fentanyl for radiography with joint distractor for the diagnosis of hip dysplasia. Fifteen healthy dogs, German Shepherd and Belgian Shepherd, were randomly submitted to treatments 0.2 mg/kg xylazine + 2.5 µg/kg fentanyl (XF) or 2 µg/kg dexmedetomidine + 2.5 µg/kg fentanyl (DF), intravenously. HR, f, SAP, MAP, DAP and TR were evaluated at intervals of 5 min before and after the administration of treatments; pH, PaCO2, PaO2, BE, HCO3−, SaO2, Na+, K+ and Hb at 5 and 15 min after treatment administration; and the quality of sedation at intervals of 5 min after administration of treatments. Latency, duration, and recovery times were also compared. The HR values showed a significant reduction in both groups, as well as pH, PaCO2, PaO2 and SaO2. Latency, duration and recovery times, and quality of sedation did not differ statistically between groups. Xylazine and fentanyl or dexmedetomidine and fentanyl combinations provide adequate sedation and analgesia for performing diagnostic radiographic procedures for hip dysplasia. However, oxygen supplementation is recommended to increase protocol safety.http://www.sciencedirect.com/science/article/pii/S2451943X2300011XAnalgesiaBlood gas analysisOxygen inhalation therapyRadiographySedation |
| spellingShingle | Suzane Lilian Beier Marcos Paulo Antunes de Lima Felipe Gaia de Sousa Renata Andrade Silva Natália Fagundes Milena Fascina Bovi Renato Cesar Sacchetto Tôrres Comparison of two sedation protocols for diagnostic radiography in dogs with hip dysplasia Veterinary and Animal Science Analgesia Blood gas analysis Oxygen inhalation therapy Radiography Sedation |
| title | Comparison of two sedation protocols for diagnostic radiography in dogs with hip dysplasia |
| title_full | Comparison of two sedation protocols for diagnostic radiography in dogs with hip dysplasia |
| title_fullStr | Comparison of two sedation protocols for diagnostic radiography in dogs with hip dysplasia |
| title_full_unstemmed | Comparison of two sedation protocols for diagnostic radiography in dogs with hip dysplasia |
| title_short | Comparison of two sedation protocols for diagnostic radiography in dogs with hip dysplasia |
| title_sort | comparison of two sedation protocols for diagnostic radiography in dogs with hip dysplasia |
| topic | Analgesia Blood gas analysis Oxygen inhalation therapy Radiography Sedation |
| url | http://www.sciencedirect.com/science/article/pii/S2451943X2300011X |
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