Daptomycin associated eosinophilic pneumonia: case report and differential diagnoses
Daptomycin is a bactericidal antibiotic approved for treatment of gram-positive skin and soft tissue infections. We present a case of an 89-year-old man who presented with fever, shortness of breath and nonproductive cough on week 4 of starting daptomycin for infective endocarditis. Computerized tom...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Greater Baltimore Medical Center
2018-05-01
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| Series: | Journal of Community Hospital Internal Medicine Perspectives |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/20009666.2018.1475188 |
| _version_ | 1797965476988452864 |
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| author | Sijan Basnet Niranjan Tachamo Rashmi Dhital Biswaraj Tharu |
| author_facet | Sijan Basnet Niranjan Tachamo Rashmi Dhital Biswaraj Tharu |
| author_sort | Sijan Basnet |
| collection | DOAJ |
| description | Daptomycin is a bactericidal antibiotic approved for treatment of gram-positive skin and soft tissue infections. We present a case of an 89-year-old man who presented with fever, shortness of breath and nonproductive cough on week 4 of starting daptomycin for infective endocarditis. Computerized tomography scan showed bilateral interstitial infiltrates predominantly affecting the lower lobes. He also had peripheral eosinophilia of 6%. He was diagnosed with eosinophilic pneumonia secondary to daptomycin use. His symptoms improved with discontinuation of daptomycin and initiation of corticosteroids. Clinical correlation of pneumonia-like presentation with recent use of daptomycin should make physicians rule out this rare adverse effect for early institution of correct treatment. |
| first_indexed | 2024-04-11T02:00:33Z |
| format | Article |
| id | doaj.art-4c2f24fc615b4b8fb5092ea0cdb3e26e |
| institution | Directory Open Access Journal |
| issn | 2000-9666 |
| language | English |
| last_indexed | 2024-04-11T02:00:33Z |
| publishDate | 2018-05-01 |
| publisher | Greater Baltimore Medical Center |
| record_format | Article |
| series | Journal of Community Hospital Internal Medicine Perspectives |
| spelling | doaj.art-4c2f24fc615b4b8fb5092ea0cdb3e26e2023-01-03T04:12:57ZengGreater Baltimore Medical CenterJournal of Community Hospital Internal Medicine Perspectives2000-96662018-05-018315215510.1080/20009666.2018.14751881475188Daptomycin associated eosinophilic pneumonia: case report and differential diagnosesSijan Basnet0Niranjan Tachamo1Rashmi Dhital2Biswaraj Tharu3Reading Hospital and Medical CenterReading Hospital and Medical CenterReading Hospital and Medical CenterTribhuvan UniversityDaptomycin is a bactericidal antibiotic approved for treatment of gram-positive skin and soft tissue infections. We present a case of an 89-year-old man who presented with fever, shortness of breath and nonproductive cough on week 4 of starting daptomycin for infective endocarditis. Computerized tomography scan showed bilateral interstitial infiltrates predominantly affecting the lower lobes. He also had peripheral eosinophilia of 6%. He was diagnosed with eosinophilic pneumonia secondary to daptomycin use. His symptoms improved with discontinuation of daptomycin and initiation of corticosteroids. Clinical correlation of pneumonia-like presentation with recent use of daptomycin should make physicians rule out this rare adverse effect for early institution of correct treatment.http://dx.doi.org/10.1080/20009666.2018.1475188Daptomycineosinophilic pneumoniaadverse effect |
| spellingShingle | Sijan Basnet Niranjan Tachamo Rashmi Dhital Biswaraj Tharu Daptomycin associated eosinophilic pneumonia: case report and differential diagnoses Journal of Community Hospital Internal Medicine Perspectives Daptomycin eosinophilic pneumonia adverse effect |
| title | Daptomycin associated eosinophilic pneumonia: case report and differential diagnoses |
| title_full | Daptomycin associated eosinophilic pneumonia: case report and differential diagnoses |
| title_fullStr | Daptomycin associated eosinophilic pneumonia: case report and differential diagnoses |
| title_full_unstemmed | Daptomycin associated eosinophilic pneumonia: case report and differential diagnoses |
| title_short | Daptomycin associated eosinophilic pneumonia: case report and differential diagnoses |
| title_sort | daptomycin associated eosinophilic pneumonia case report and differential diagnoses |
| topic | Daptomycin eosinophilic pneumonia adverse effect |
| url | http://dx.doi.org/10.1080/20009666.2018.1475188 |
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