Increased <i>Demodex</i> Density in Patients Hospitalized for Worsening Heart Failure
Infection is an important factor leading to the exacerbation of heart failure (HF), resulting in hospitalization. <i>Demodex</i> species are obligatory parasites in human skin, and increased density was reported in immunocompromised patients. In this study, we aimed to investigate the &l...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-05-01
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| Series: | Journal of Personalized Medicine |
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| Online Access: | https://www.mdpi.com/2075-4426/10/2/39 |
| _version_ | 1797568155081506816 |
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| author | Serkan Yüksel Esra Pancar Yüksel |
| author_facet | Serkan Yüksel Esra Pancar Yüksel |
| author_sort | Serkan Yüksel |
| collection | DOAJ |
| description | Infection is an important factor leading to the exacerbation of heart failure (HF), resulting in hospitalization. <i>Demodex</i> species are obligatory parasites in human skin, and increased density was reported in immunocompromised patients. In this study, we aimed to investigate the <i>Demodex</i> density in hospitalized HF patients compared to that of healthy controls. Methods: This study included 36 HF patients and 36 age and sex-matched healthy controls. Five standardized biopsies were taken from the face of participants and assessed for <i>Demodex</i> by a light microscope. Results: At least one <i>Demodex</i> mite was detected in 20 HF patients and nine of the control group. The number of <i>Demodex</i> mites was significantly higher in the HF group (median 1; min. 0 and max. 10) compared to the control group (median 0; minimum. 0 and maximum. 3). Demodicidosis was positive in 14 of the HF patients. Demodicidosis was not detected in the control group. Conclusions: This study showed that <i>Demodex</i> positivity is more common in HF patients hospitalized for HF exacerbation. Demodicidosis should be considered in hospitalized HF patients. |
| first_indexed | 2024-03-10T19:52:26Z |
| format | Article |
| id | doaj.art-4c305caabb144b25865bbc37c8f24cd3 |
| institution | Directory Open Access Journal |
| issn | 2075-4426 |
| language | English |
| last_indexed | 2024-03-10T19:52:26Z |
| publishDate | 2020-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Personalized Medicine |
| spelling | doaj.art-4c305caabb144b25865bbc37c8f24cd32023-11-20T00:15:53ZengMDPI AGJournal of Personalized Medicine2075-44262020-05-011023910.3390/jpm10020039Increased <i>Demodex</i> Density in Patients Hospitalized for Worsening Heart FailureSerkan Yüksel0Esra Pancar Yüksel1Cardiology Department, Faculty of Medicine, Ondokuz Mayıs University, 55139 Samsun, TurkeyDermatology Department, Faculty of Medicine, Ondokuz Mayıs University, 55139 Samsun, TurkeyInfection is an important factor leading to the exacerbation of heart failure (HF), resulting in hospitalization. <i>Demodex</i> species are obligatory parasites in human skin, and increased density was reported in immunocompromised patients. In this study, we aimed to investigate the <i>Demodex</i> density in hospitalized HF patients compared to that of healthy controls. Methods: This study included 36 HF patients and 36 age and sex-matched healthy controls. Five standardized biopsies were taken from the face of participants and assessed for <i>Demodex</i> by a light microscope. Results: At least one <i>Demodex</i> mite was detected in 20 HF patients and nine of the control group. The number of <i>Demodex</i> mites was significantly higher in the HF group (median 1; min. 0 and max. 10) compared to the control group (median 0; minimum. 0 and maximum. 3). Demodicidosis was positive in 14 of the HF patients. Demodicidosis was not detected in the control group. Conclusions: This study showed that <i>Demodex</i> positivity is more common in HF patients hospitalized for HF exacerbation. Demodicidosis should be considered in hospitalized HF patients.https://www.mdpi.com/2075-4426/10/2/39<i>Demodex</i> mitesdemodicidosisheart failureimmunosuppression |
| spellingShingle | Serkan Yüksel Esra Pancar Yüksel Increased <i>Demodex</i> Density in Patients Hospitalized for Worsening Heart Failure Journal of Personalized Medicine <i>Demodex</i> mites demodicidosis heart failure immunosuppression |
| title | Increased <i>Demodex</i> Density in Patients Hospitalized for Worsening Heart Failure |
| title_full | Increased <i>Demodex</i> Density in Patients Hospitalized for Worsening Heart Failure |
| title_fullStr | Increased <i>Demodex</i> Density in Patients Hospitalized for Worsening Heart Failure |
| title_full_unstemmed | Increased <i>Demodex</i> Density in Patients Hospitalized for Worsening Heart Failure |
| title_short | Increased <i>Demodex</i> Density in Patients Hospitalized for Worsening Heart Failure |
| title_sort | increased i demodex i density in patients hospitalized for worsening heart failure |
| topic | <i>Demodex</i> mites demodicidosis heart failure immunosuppression |
| url | https://www.mdpi.com/2075-4426/10/2/39 |
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