Cost-effectiveness analysis of the diarrhea alleviation through zinc and oral rehydration therapy (DAZT) program in rural Gujarat India: an application of the net-benefit regression framework
Abstract Background This study evaluates the cost-effectiveness of the DAZT program for scaling up treatment of acute child diarrhea in Gujarat India using a net-benefit regression framework. Methods Costs were calculated from societal and caregivers’ perspectives and effectiveness was assessed in t...
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| Format: | Article |
| Language: | English |
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BMC
2017-06-01
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| Series: | Cost Effectiveness and Resource Allocation |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12962-017-0070-y |
| _version_ | 1819016035508944896 |
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| author | Samuel D. Shillcutt Amnesty E. LeFevre Christa L. Fischer-Walker Sunita Taneja Robert E. Black Sarmila Mazumder |
| author_facet | Samuel D. Shillcutt Amnesty E. LeFevre Christa L. Fischer-Walker Sunita Taneja Robert E. Black Sarmila Mazumder |
| author_sort | Samuel D. Shillcutt |
| collection | DOAJ |
| description | Abstract Background This study evaluates the cost-effectiveness of the DAZT program for scaling up treatment of acute child diarrhea in Gujarat India using a net-benefit regression framework. Methods Costs were calculated from societal and caregivers’ perspectives and effectiveness was assessed in terms of coverage of zinc and both zinc and Oral Rehydration Salt. Regression models were tested in simple linear regression, with a specified set of covariates, and with a specified set of covariates and interaction terms using linear regression with endogenous treatment effects was used as the reference case. Results The DAZT program was cost-effective with over 95% certainty above $5.50 and $7.50 per appropriately treated child in the unadjusted and adjusted models respectively, with specifications including interaction terms being cost-effective with 85–97% certainty. Discussion Findings from this study should be combined with other evidence when considering decisions to scale up programs such as the DAZT program to promote the use of ORS and zinc to treat child diarrhea. |
| first_indexed | 2024-12-21T02:41:14Z |
| format | Article |
| id | doaj.art-4c34693fd4084435859beacae121ce99 |
| institution | Directory Open Access Journal |
| issn | 1478-7547 |
| language | English |
| last_indexed | 2024-12-21T02:41:14Z |
| publishDate | 2017-06-01 |
| publisher | BMC |
| record_format | Article |
| series | Cost Effectiveness and Resource Allocation |
| spelling | doaj.art-4c34693fd4084435859beacae121ce992022-12-21T19:18:40ZengBMCCost Effectiveness and Resource Allocation1478-75472017-06-0115111510.1186/s12962-017-0070-yCost-effectiveness analysis of the diarrhea alleviation through zinc and oral rehydration therapy (DAZT) program in rural Gujarat India: an application of the net-benefit regression frameworkSamuel D. Shillcutt0Amnesty E. LeFevre1Christa L. Fischer-Walker2Sunita Taneja3Robert E. Black4Sarmila Mazumder5Department of International Health, Johns Hopkins Bloomberg School of Public HealthDepartment of International Health, Johns Hopkins Bloomberg School of Public HealthDepartment of International Health, Johns Hopkins Bloomberg School of Public HealthCentre for Health Research and Development, Society for Applied StudiesDepartment of International Health, Johns Hopkins Bloomberg School of Public HealthCentre for Health Research and Development, Society for Applied StudiesAbstract Background This study evaluates the cost-effectiveness of the DAZT program for scaling up treatment of acute child diarrhea in Gujarat India using a net-benefit regression framework. Methods Costs were calculated from societal and caregivers’ perspectives and effectiveness was assessed in terms of coverage of zinc and both zinc and Oral Rehydration Salt. Regression models were tested in simple linear regression, with a specified set of covariates, and with a specified set of covariates and interaction terms using linear regression with endogenous treatment effects was used as the reference case. Results The DAZT program was cost-effective with over 95% certainty above $5.50 and $7.50 per appropriately treated child in the unadjusted and adjusted models respectively, with specifications including interaction terms being cost-effective with 85–97% certainty. Discussion Findings from this study should be combined with other evidence when considering decisions to scale up programs such as the DAZT program to promote the use of ORS and zinc to treat child diarrhea.http://link.springer.com/article/10.1186/s12962-017-0070-yDiarrheaCost-effectivenessNet-benefit regressionZincOral rehydration saltsIndia |
| spellingShingle | Samuel D. Shillcutt Amnesty E. LeFevre Christa L. Fischer-Walker Sunita Taneja Robert E. Black Sarmila Mazumder Cost-effectiveness analysis of the diarrhea alleviation through zinc and oral rehydration therapy (DAZT) program in rural Gujarat India: an application of the net-benefit regression framework Cost Effectiveness and Resource Allocation Diarrhea Cost-effectiveness Net-benefit regression Zinc Oral rehydration salts India |
| title | Cost-effectiveness analysis of the diarrhea alleviation through zinc and oral rehydration therapy (DAZT) program in rural Gujarat India: an application of the net-benefit regression framework |
| title_full | Cost-effectiveness analysis of the diarrhea alleviation through zinc and oral rehydration therapy (DAZT) program in rural Gujarat India: an application of the net-benefit regression framework |
| title_fullStr | Cost-effectiveness analysis of the diarrhea alleviation through zinc and oral rehydration therapy (DAZT) program in rural Gujarat India: an application of the net-benefit regression framework |
| title_full_unstemmed | Cost-effectiveness analysis of the diarrhea alleviation through zinc and oral rehydration therapy (DAZT) program in rural Gujarat India: an application of the net-benefit regression framework |
| title_short | Cost-effectiveness analysis of the diarrhea alleviation through zinc and oral rehydration therapy (DAZT) program in rural Gujarat India: an application of the net-benefit regression framework |
| title_sort | cost effectiveness analysis of the diarrhea alleviation through zinc and oral rehydration therapy dazt program in rural gujarat india an application of the net benefit regression framework |
| topic | Diarrhea Cost-effectiveness Net-benefit regression Zinc Oral rehydration salts India |
| url | http://link.springer.com/article/10.1186/s12962-017-0070-y |
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