Persistent anemia in a kidney transplant recipient with parvovirus B19 infection
Anemia after kidney transplant is not uncommon. This paper reports a case of unexplained anemia in a kidney transplant recipient that persisted for more than two months, and that did not respond to recombinant human erythropoietin treatment but was successfully treated after diagnosing Parvovirus B1...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2017-01-01
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| Series: | Saudi Journal of Kidney Diseases and Transplantation |
| Online Access: | http://www.sjkdt.org/article.asp?issn=1319-2442;year=2017;volume=28;issue=6;spage=1447;epage=1450;aulast=Pakkyara |
| _version_ | 1811193360326590464 |
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| author | Abbas Pakkyara Amitabh Jha Issa Al Salmi Wasim A Siddiqi Nasser Al Rahbi Arundhati P Kurkulasurya Jalila Mohsin |
| author_facet | Abbas Pakkyara Amitabh Jha Issa Al Salmi Wasim A Siddiqi Nasser Al Rahbi Arundhati P Kurkulasurya Jalila Mohsin |
| author_sort | Abbas Pakkyara |
| collection | DOAJ |
| description | Anemia after kidney transplant is not uncommon. This paper reports a case of unexplained anemia in a kidney transplant recipient that persisted for more than two months, and that did not respond to recombinant human erythropoietin treatment but was successfully treated after diagnosing Parvovirus B19 (ParvoV B19) infection. A middle-aged male underwent living-unrelated kidney transplantation from Pakistan in April 2015. He was on triple immuno-suppression therapy consisting of prednisolone, tacrolimus, and mycophenolate mofetil. He presented with anemia which persisted for more than two months that did not improve with Darbepoetin alpha and required blood transfusions. A bone marrow biopsy demonstrated pure erythroid hypoplasia and occasional giant pronormoblasts characteristic of a ParvoV B19 infection. The serum was highly positive for ParvoV B19 DNA polymerase chain reaction. The anemia resolved completely three weeks after the administration of intravenous immunoglobulin. ParvoV B19 infection should be considered in the differential diagnosis of kidney transplant recipients who present with anemia associated with a low reticulocyte count. |
| first_indexed | 2024-04-12T00:08:07Z |
| format | Article |
| id | doaj.art-4c38fe4fa5474b038500dbc96cef1d1f |
| institution | Directory Open Access Journal |
| issn | 1319-2442 |
| language | English |
| last_indexed | 2024-04-12T00:08:07Z |
| publishDate | 2017-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Saudi Journal of Kidney Diseases and Transplantation |
| spelling | doaj.art-4c38fe4fa5474b038500dbc96cef1d1f2022-12-22T03:56:03ZengWolters Kluwer Medknow PublicationsSaudi Journal of Kidney Diseases and Transplantation1319-24422017-01-012861447145010.4103/1319-2442.220846Persistent anemia in a kidney transplant recipient with parvovirus B19 infectionAbbas PakkyaraAmitabh JhaIssa Al SalmiWasim A SiddiqiNasser Al RahbiArundhati P KurkulasuryaJalila MohsinAnemia after kidney transplant is not uncommon. This paper reports a case of unexplained anemia in a kidney transplant recipient that persisted for more than two months, and that did not respond to recombinant human erythropoietin treatment but was successfully treated after diagnosing Parvovirus B19 (ParvoV B19) infection. A middle-aged male underwent living-unrelated kidney transplantation from Pakistan in April 2015. He was on triple immuno-suppression therapy consisting of prednisolone, tacrolimus, and mycophenolate mofetil. He presented with anemia which persisted for more than two months that did not improve with Darbepoetin alpha and required blood transfusions. A bone marrow biopsy demonstrated pure erythroid hypoplasia and occasional giant pronormoblasts characteristic of a ParvoV B19 infection. The serum was highly positive for ParvoV B19 DNA polymerase chain reaction. The anemia resolved completely three weeks after the administration of intravenous immunoglobulin. ParvoV B19 infection should be considered in the differential diagnosis of kidney transplant recipients who present with anemia associated with a low reticulocyte count.http://www.sjkdt.org/article.asp?issn=1319-2442;year=2017;volume=28;issue=6;spage=1447;epage=1450;aulast=Pakkyara |
| spellingShingle | Abbas Pakkyara Amitabh Jha Issa Al Salmi Wasim A Siddiqi Nasser Al Rahbi Arundhati P Kurkulasurya Jalila Mohsin Persistent anemia in a kidney transplant recipient with parvovirus B19 infection Saudi Journal of Kidney Diseases and Transplantation |
| title | Persistent anemia in a kidney transplant recipient with parvovirus B19 infection |
| title_full | Persistent anemia in a kidney transplant recipient with parvovirus B19 infection |
| title_fullStr | Persistent anemia in a kidney transplant recipient with parvovirus B19 infection |
| title_full_unstemmed | Persistent anemia in a kidney transplant recipient with parvovirus B19 infection |
| title_short | Persistent anemia in a kidney transplant recipient with parvovirus B19 infection |
| title_sort | persistent anemia in a kidney transplant recipient with parvovirus b19 infection |
| url | http://www.sjkdt.org/article.asp?issn=1319-2442;year=2017;volume=28;issue=6;spage=1447;epage=1450;aulast=Pakkyara |
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