Extraesophageal manifestations of gastroesophageal reflux disease: cough, asthma, laryngitis, chest pain
Gastroesophageal reflux is a common condition affecting many patients in different parts of the world. It usually presents with the classic manifestations of heartburn and regurgitation; however, in some it can also present with extraesophageal manifestations such as chronic cough, laryngitis,...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
SMW supporting association (Trägerverein Swiss Medical Weekly SMW)
2012-03-01
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| Series: | Swiss Medical Weekly |
| Subjects: | |
| Online Access: | https://www.smw.ch/index.php/smw/article/view/1450 |
| _version_ | 1811288901658083328 |
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| author | Elif Saritas Yuksel Michael Vaezi |
| author_facet | Elif Saritas Yuksel Michael Vaezi |
| author_sort | Elif Saritas Yuksel |
| collection | DOAJ |
| description |
Gastroesophageal reflux is a common condition affecting many patients in different parts of the world. It usually presents with the classic manifestations of heartburn and regurgitation; however, in some it can also present with extraesophageal manifestations such as chronic cough, laryngitis, asthma or chest pain. Commonly employed diagnostic tests such as esophagogastroduodenoscopy and ambulatory pH or impedance monitoring in gastroesophageal reflux, are less useful in extraesophageal syndromes due to their poor sensitivity and specificity. In contrast, empiric trials of PPI’s are shown to be cost effective; however, patients may require long-term treatment to establish effectiveness. Diagnostic testing with pH and impedance monitoring are commonly reserved for patients with partial or poor response to the initial treatment with PPI’s. Poor response to PPI therapy may be an important indicator for non-gastroesophageal reflux causes for patients’ symptoms and should initiate a search for other potential causes.
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| first_indexed | 2024-04-13T03:45:40Z |
| format | Article |
| id | doaj.art-4c39255374264107a71acb1e370b09be |
| institution | Directory Open Access Journal |
| issn | 1424-3997 |
| language | English |
| last_indexed | 2024-04-13T03:45:40Z |
| publishDate | 2012-03-01 |
| publisher | SMW supporting association (Trägerverein Swiss Medical Weekly SMW) |
| record_format | Article |
| series | Swiss Medical Weekly |
| spelling | doaj.art-4c39255374264107a71acb1e370b09be2022-12-22T03:04:01ZengSMW supporting association (Trägerverein Swiss Medical Weekly SMW)Swiss Medical Weekly1424-39972012-03-01142111210.4414/smw.2012.13544Extraesophageal manifestations of gastroesophageal reflux disease: cough, asthma, laryngitis, chest painElif Saritas YukselMichael Vaezi Gastroesophageal reflux is a common condition affecting many patients in different parts of the world. It usually presents with the classic manifestations of heartburn and regurgitation; however, in some it can also present with extraesophageal manifestations such as chronic cough, laryngitis, asthma or chest pain. Commonly employed diagnostic tests such as esophagogastroduodenoscopy and ambulatory pH or impedance monitoring in gastroesophageal reflux, are less useful in extraesophageal syndromes due to their poor sensitivity and specificity. In contrast, empiric trials of PPI’s are shown to be cost effective; however, patients may require long-term treatment to establish effectiveness. Diagnostic testing with pH and impedance monitoring are commonly reserved for patients with partial or poor response to the initial treatment with PPI’s. Poor response to PPI therapy may be an important indicator for non-gastroesophageal reflux causes for patients’ symptoms and should initiate a search for other potential causes. https://www.smw.ch/index.php/smw/article/view/1450AsthmaChronic coughchronic laryngitisextraesophageal reflux syndromeReflux |
| spellingShingle | Elif Saritas Yuksel Michael Vaezi Extraesophageal manifestations of gastroesophageal reflux disease: cough, asthma, laryngitis, chest pain Swiss Medical Weekly Asthma Chronic cough chronic laryngitis extraesophageal reflux syndrome Reflux |
| title | Extraesophageal manifestations of gastroesophageal reflux disease: cough, asthma, laryngitis, chest pain |
| title_full | Extraesophageal manifestations of gastroesophageal reflux disease: cough, asthma, laryngitis, chest pain |
| title_fullStr | Extraesophageal manifestations of gastroesophageal reflux disease: cough, asthma, laryngitis, chest pain |
| title_full_unstemmed | Extraesophageal manifestations of gastroesophageal reflux disease: cough, asthma, laryngitis, chest pain |
| title_short | Extraesophageal manifestations of gastroesophageal reflux disease: cough, asthma, laryngitis, chest pain |
| title_sort | extraesophageal manifestations of gastroesophageal reflux disease cough asthma laryngitis chest pain |
| topic | Asthma Chronic cough chronic laryngitis extraesophageal reflux syndrome Reflux |
| url | https://www.smw.ch/index.php/smw/article/view/1450 |
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