Positive schizotypy is associated with amplified mnemonic discrimination and attenuated generalization

Introduction Tendency to experience inaccurate beliefs alongside perceptual anomalies constitutes positive schizotypal traits in the general population and shows continuity with the positive symptoms of schizophrenia. It has been hypothesized that the positive symptomatology of schizophrenia, and b...

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Main Authors: Á. Vass, M. Becske, Á. Szőllősi, M. Racsmány, B. Polner
Format: Article
Language:English
Published: Cambridge University Press 2022-06-01
Series:European Psychiatry
Subjects:
Online Access:https://www.cambridge.org/core/product/identifier/S0924933822004096/type/journal_article
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author Á. Vass
M. Becske
Á. Szőllősi
M. Racsmány
B. Polner
author_facet Á. Vass
M. Becske
Á. Szőllősi
M. Racsmány
B. Polner
author_sort Á. Vass
collection DOAJ
description Introduction Tendency to experience inaccurate beliefs alongside perceptual anomalies constitutes positive schizotypal traits in the general population and shows continuity with the positive symptoms of schizophrenia. It has been hypothesized that the positive symptomatology of schizophrenia, and by extension, positive schizotypy, are associated with specific alterations in memory functions. Imbalance between memory generalization and episodic memory specificity has been proposed on several counts; however, the direction of the imbalance is currently unclear. Objectives We aimed to contrast two competing hypotheses regarding the association between positive schizotypy, and memory alterations in a general population sample (N=71) enriched for positive schizotypy from a larger pool of individuals (N=614). Methods Positive schizotypy was measured with the short-version of the O-LIFE questionnaire, and memory specificity and generalization was captured by the well-established Mnemonic Similarity Task. Results Distortions in the behavioural memory performance indices were found to correlate with positive schizotypy: individuals prone to unusual experiences demonstrated increased discrimination and reduced generalization (explaining 10% and 17% of variance, respectively). Associations were robust when controlled for the disorganized, negative and impulsive-asocial dimensions of schizotypy and associated psychopathology. Conclusions Our findings show that people who are prone to irrational beliefs and unusual experiences also show measurable alterations in memory and likely have difficulty grasping the global picture and rather be overpowered by fragments of information. Disclosure No significant relationships.
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spelling doaj.art-4c3972cf538e4cd3ad4a76a9ca64d4772023-11-17T05:08:18ZengCambridge University PressEuropean Psychiatry0924-93381778-35852022-06-0165S152S15210.1192/j.eurpsy.2022.409Positive schizotypy is associated with amplified mnemonic discrimination and attenuated generalizationÁ. Vass0M. Becske1Á. Szőllősi2M. Racsmány3B. Polner4Semmelweis University, Department Of Psychiatry And Psychotherapy, Budapest, HungarySemmelweis University, Department Of Psychiatry And Psychotherapy, Budapest, HungaryBudapest University of Technology and Economics, Department Of Cognitive Science, Budapest, Hungary Research Centre for Natural Sciences, Institute Of Cognitive Neuroscience And Psychology, Budapest, HungaryBudapest University of Technology and Economics, Department Of Cognitive Science, Budapest, Hungary Research Centre for Natural Sciences, Institute Of Cognitive Neuroscience And Psychology, Budapest, HungaryBudapest University of Technology and Economics, Department Of Cognitive Science, Budapest, Hungary Introduction Tendency to experience inaccurate beliefs alongside perceptual anomalies constitutes positive schizotypal traits in the general population and shows continuity with the positive symptoms of schizophrenia. It has been hypothesized that the positive symptomatology of schizophrenia, and by extension, positive schizotypy, are associated with specific alterations in memory functions. Imbalance between memory generalization and episodic memory specificity has been proposed on several counts; however, the direction of the imbalance is currently unclear. Objectives We aimed to contrast two competing hypotheses regarding the association between positive schizotypy, and memory alterations in a general population sample (N=71) enriched for positive schizotypy from a larger pool of individuals (N=614). Methods Positive schizotypy was measured with the short-version of the O-LIFE questionnaire, and memory specificity and generalization was captured by the well-established Mnemonic Similarity Task. Results Distortions in the behavioural memory performance indices were found to correlate with positive schizotypy: individuals prone to unusual experiences demonstrated increased discrimination and reduced generalization (explaining 10% and 17% of variance, respectively). Associations were robust when controlled for the disorganized, negative and impulsive-asocial dimensions of schizotypy and associated psychopathology. Conclusions Our findings show that people who are prone to irrational beliefs and unusual experiences also show measurable alterations in memory and likely have difficulty grasping the global picture and rather be overpowered by fragments of information. Disclosure No significant relationships. https://www.cambridge.org/core/product/identifier/S0924933822004096/type/journal_articleepisodic memoryschizotypypattern separationpattern completion
spellingShingle Á. Vass
M. Becske
Á. Szőllősi
M. Racsmány
B. Polner
Positive schizotypy is associated with amplified mnemonic discrimination and attenuated generalization
European Psychiatry
episodic memory
schizotypy
pattern separation
pattern completion
title Positive schizotypy is associated with amplified mnemonic discrimination and attenuated generalization
title_full Positive schizotypy is associated with amplified mnemonic discrimination and attenuated generalization
title_fullStr Positive schizotypy is associated with amplified mnemonic discrimination and attenuated generalization
title_full_unstemmed Positive schizotypy is associated with amplified mnemonic discrimination and attenuated generalization
title_short Positive schizotypy is associated with amplified mnemonic discrimination and attenuated generalization
title_sort positive schizotypy is associated with amplified mnemonic discrimination and attenuated generalization
topic episodic memory
schizotypy
pattern separation
pattern completion
url https://www.cambridge.org/core/product/identifier/S0924933822004096/type/journal_article
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