Endurance Training Depletes Antioxidant System but Does Not Affect Endothelial Functions in Women with Abdominal Obesity: A Randomized Trial with a Comparison to Endurance-Strength Training
Limited data suggested that inclusion of a strength component into endurance exercises might intensify the beneficial effect of training. However, the available data is limited. Therefore, we aimed to compare the effect of endurance and endurance-strength training on anthropometric parameters, endot...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-04-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/10/8/1639 |
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| author | Małgorzata Jamka Paweł Bogdański Patrycja Krzyżanowska-Jankowska Anna Miśkiewicz-Chotnicka Joanna Karolkiewicz Monika Duś-Żuchowska Radosław Mądry Aleksandra Lisowska Anna Gotz-Więckowska Saule Iskakova Jarosław Walkowiak Edyta Mądry |
| author_facet | Małgorzata Jamka Paweł Bogdański Patrycja Krzyżanowska-Jankowska Anna Miśkiewicz-Chotnicka Joanna Karolkiewicz Monika Duś-Żuchowska Radosław Mądry Aleksandra Lisowska Anna Gotz-Więckowska Saule Iskakova Jarosław Walkowiak Edyta Mądry |
| author_sort | Małgorzata Jamka |
| collection | DOAJ |
| description | Limited data suggested that inclusion of a strength component into endurance exercises might intensify the beneficial effect of training. However, the available data is limited. Therefore, we aimed to compare the effect of endurance and endurance-strength training on anthropometric parameters, endothelial function, arterial stiffness, antioxidant status, and inflammatory markers in abdominally obese women without serious comorbidities. A total of 101 women were recruited and randomly divided into endurance (<i>n</i> = 52) and endurance-strength (<i>n</i> = 49) groups. During the three-month intervention, both groups performed supervised sixty-minute training three times a week. All studied parameters were measured pre- and post-intervention period. In total, 85 women completed the study. Both training significantly decreased anthropometric parameters. Besides, endurance training decreased endothelial nitric oxide synthase, central aortic systolic pressure, pulse wave velocity, glutathione (GSH), total antioxidant status (TAS), interleukin (IL) 8, matrix metalloproteinase (MMP) 9, and tumor necrosis factor alpha, while endurance-strength training decreased MMP-2 concentrations, and increased IL-6, monocyte chemoattractant protein-1, and MMP-9 levels. We observed significant differences between groups for GSH, TAS, and MMP-9 levels. In summary, endurance and endurance-strength training did not differ in the impact on endothelial function and arterial stiffness. However, endurance training significantly depleted the antioxidant defense, simultaneously reducing MMP-9 levels. The study was retrospectively registered with the German Clinical Trials Register within the number DRKS00019832. |
| first_indexed | 2024-03-10T12:23:06Z |
| format | Article |
| id | doaj.art-4c3b3a40d46e42778b4cb5fdda30d44a |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-10T12:23:06Z |
| publishDate | 2021-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-4c3b3a40d46e42778b4cb5fdda30d44a2023-11-21T15:15:44ZengMDPI AGJournal of Clinical Medicine2077-03832021-04-01108163910.3390/jcm10081639Endurance Training Depletes Antioxidant System but Does Not Affect Endothelial Functions in Women with Abdominal Obesity: A Randomized Trial with a Comparison to Endurance-Strength TrainingMałgorzata Jamka0Paweł Bogdański1Patrycja Krzyżanowska-Jankowska2Anna Miśkiewicz-Chotnicka3Joanna Karolkiewicz4Monika Duś-Żuchowska5Radosław Mądry6Aleksandra Lisowska7Anna Gotz-Więckowska8Saule Iskakova9Jarosław Walkowiak10Edyta Mądry11Department of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, Szpitalna Str. 27/33, 60-572 Poznań, PolandDepartment of Treatment of Obesity, Metabolic Disorders and Clinical Dietetics, Poznan University of Medical Sciences, Szamarzewskiego Str. 82, 60-569 Poznań, PolandDepartment of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, Szpitalna Str. 27/33, 60-572 Poznań, PolandDepartment of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, Szpitalna Str. 27/33, 60-572 Poznań, PolandDepartment of Food and Nutrition, Poznan University of Physical Education, Królowej Jadwigi Str. 27/39, 61-871 Poznań, PolandDepartment of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, Szpitalna Str. 27/33, 60-572 Poznań, PolandDepartment of Oncology, Poznan University of Medical Sciences, Szamarzewskiego Str. 84, 60-569 Poznań, PolandDepartment of Clinical Auxology and Pediatric Nursing, Poznan University of Medical Sciences, Szpitalna Str. 27/33, 60-572 Poznań, PolandDepartment of Ophthalmology, Poznan University of Medical Sciences, Szamarzewskiego Str. 84, 60-569 Poznań, PolandDepartment of Pharmacology, Asfendiyarov Kazakh National Medical University, Tole Bi Str. 94, Almaty 050000, KazakhstanDepartment of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, Szpitalna Str. 27/33, 60-572 Poznań, PolandDepartment of Physiology, Poznan University of Medical Sciences, Święcickiego Str. 6, 60-781 Poznań, PolandLimited data suggested that inclusion of a strength component into endurance exercises might intensify the beneficial effect of training. However, the available data is limited. Therefore, we aimed to compare the effect of endurance and endurance-strength training on anthropometric parameters, endothelial function, arterial stiffness, antioxidant status, and inflammatory markers in abdominally obese women without serious comorbidities. A total of 101 women were recruited and randomly divided into endurance (<i>n</i> = 52) and endurance-strength (<i>n</i> = 49) groups. During the three-month intervention, both groups performed supervised sixty-minute training three times a week. All studied parameters were measured pre- and post-intervention period. In total, 85 women completed the study. Both training significantly decreased anthropometric parameters. Besides, endurance training decreased endothelial nitric oxide synthase, central aortic systolic pressure, pulse wave velocity, glutathione (GSH), total antioxidant status (TAS), interleukin (IL) 8, matrix metalloproteinase (MMP) 9, and tumor necrosis factor alpha, while endurance-strength training decreased MMP-2 concentrations, and increased IL-6, monocyte chemoattractant protein-1, and MMP-9 levels. We observed significant differences between groups for GSH, TAS, and MMP-9 levels. In summary, endurance and endurance-strength training did not differ in the impact on endothelial function and arterial stiffness. However, endurance training significantly depleted the antioxidant defense, simultaneously reducing MMP-9 levels. The study was retrospectively registered with the German Clinical Trials Register within the number DRKS00019832.https://www.mdpi.com/2077-0383/10/8/1639antioxidant statusoxidative stressinflammatory markerscardiovascular risk |
| spellingShingle | Małgorzata Jamka Paweł Bogdański Patrycja Krzyżanowska-Jankowska Anna Miśkiewicz-Chotnicka Joanna Karolkiewicz Monika Duś-Żuchowska Radosław Mądry Aleksandra Lisowska Anna Gotz-Więckowska Saule Iskakova Jarosław Walkowiak Edyta Mądry Endurance Training Depletes Antioxidant System but Does Not Affect Endothelial Functions in Women with Abdominal Obesity: A Randomized Trial with a Comparison to Endurance-Strength Training Journal of Clinical Medicine antioxidant status oxidative stress inflammatory markers cardiovascular risk |
| title | Endurance Training Depletes Antioxidant System but Does Not Affect Endothelial Functions in Women with Abdominal Obesity: A Randomized Trial with a Comparison to Endurance-Strength Training |
| title_full | Endurance Training Depletes Antioxidant System but Does Not Affect Endothelial Functions in Women with Abdominal Obesity: A Randomized Trial with a Comparison to Endurance-Strength Training |
| title_fullStr | Endurance Training Depletes Antioxidant System but Does Not Affect Endothelial Functions in Women with Abdominal Obesity: A Randomized Trial with a Comparison to Endurance-Strength Training |
| title_full_unstemmed | Endurance Training Depletes Antioxidant System but Does Not Affect Endothelial Functions in Women with Abdominal Obesity: A Randomized Trial with a Comparison to Endurance-Strength Training |
| title_short | Endurance Training Depletes Antioxidant System but Does Not Affect Endothelial Functions in Women with Abdominal Obesity: A Randomized Trial with a Comparison to Endurance-Strength Training |
| title_sort | endurance training depletes antioxidant system but does not affect endothelial functions in women with abdominal obesity a randomized trial with a comparison to endurance strength training |
| topic | antioxidant status oxidative stress inflammatory markers cardiovascular risk |
| url | https://www.mdpi.com/2077-0383/10/8/1639 |
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