Phytomedicinal properties of Hygrophila schulli (Neeramulliya)

Hygrophila schulli which is known as “Neermulli’’ in the vernacular is an herbaceous plant native to Sri Lanka. Ancient medicinal literature suggests the use of H. schulli whole plant or its parts for the treatment of different communicable and non-communicable diseases including diabetes mellitus a...

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Main Authors: Malshani Nissanka, Manjula Weerasekera, Ayomi Dilhari, Ranga Dissanayake, Sajeewa Rathnayake, Gayan Wijesinghe
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2023-09-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:https://ijbms.mums.ac.ir/article_22295_1a2ea94d316da57989ab62f9169afb2e.pdf
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author Malshani Nissanka
Manjula Weerasekera
Ayomi Dilhari
Ranga Dissanayake
Sajeewa Rathnayake
Gayan Wijesinghe
author_facet Malshani Nissanka
Manjula Weerasekera
Ayomi Dilhari
Ranga Dissanayake
Sajeewa Rathnayake
Gayan Wijesinghe
author_sort Malshani Nissanka
collection DOAJ
description Hygrophila schulli which is known as “Neermulli’’ in the vernacular is an herbaceous plant native to Sri Lanka. Ancient medicinal literature suggests the use of H. schulli whole plant or its parts for the treatment of different communicable and non-communicable diseases including diabetes mellitus and tuberculosis. Active constituents and secondary metabolites including alkaloids, tannins, steroids, proteins, flavonoids, and glycosides are identified to possess antimicrobial, antitumor, antioxidant, hepatoprotective, anthelmintic, nephroprotective, antidiabetic, anticataract, anti-inflammatory, anti-nociceptive, hematopoietic, diuretic, antiurolithiatic, antipyretic, neuroprotection, and anti-endotoxin activities. In this review, we reviewed clinical studies, patents, and analytical studies from the earliest found examples from 1886 to the end of 2021. We critically analyzed and attempt to summarize the information based on bioactivities and chemical composition of H. schulli plant extracts which will be of future use for researchers in this field.
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spelling doaj.art-4c3b6b80b15e405baffa0d67aacbe8a12023-09-17T06:57:15ZengMashhad University of Medical SciencesIranian Journal of Basic Medical Sciences2008-38662008-38742023-09-0126997998610.22038/ijbms.2023.67965.1487722295Phytomedicinal properties of Hygrophila schulli (Neeramulliya)Malshani Nissanka0Manjula Weerasekera1Ayomi Dilhari2Ranga Dissanayake3Sajeewa Rathnayake4Gayan Wijesinghe5Department of Microbiology, Faculty of Medical Sciences, University of Sri Jayewardenepura, Nugegoda, Sri LankaDepartment of Microbiology, Faculty of Medical Sciences, University of Sri Jayewardenepura, Nugegoda, Sri LankaDepartment of Basic Sciences, Faculty of Allied Health Sciences, University of Sri Jayewardenepura, Nugegoda, Sri LankaDepartment of Pharmacy and Pharmaceutical Sciences, Faculty of Allied Health Sciences, University of Sri Jayewardenepura, Nugegoda, Sri LankaThe Centre for Infectious Diseases and Phytochemical Studies, Faculty of Integrated Life Sciences, Quest International University Perak, Perak, MalaysiaBristol Dental School, University of Bristol, United KingdomHygrophila schulli which is known as “Neermulli’’ in the vernacular is an herbaceous plant native to Sri Lanka. Ancient medicinal literature suggests the use of H. schulli whole plant or its parts for the treatment of different communicable and non-communicable diseases including diabetes mellitus and tuberculosis. Active constituents and secondary metabolites including alkaloids, tannins, steroids, proteins, flavonoids, and glycosides are identified to possess antimicrobial, antitumor, antioxidant, hepatoprotective, anthelmintic, nephroprotective, antidiabetic, anticataract, anti-inflammatory, anti-nociceptive, hematopoietic, diuretic, antiurolithiatic, antipyretic, neuroprotection, and anti-endotoxin activities. In this review, we reviewed clinical studies, patents, and analytical studies from the earliest found examples from 1886 to the end of 2021. We critically analyzed and attempt to summarize the information based on bioactivities and chemical composition of H. schulli plant extracts which will be of future use for researchers in this field.https://ijbms.mums.ac.ir/article_22295_1a2ea94d316da57989ab62f9169afb2e.pdfalkaloidsanti-bacterial agentsanti-infective agentsanti-inflammatory agentsanti-oxidantsbiodiversityplant extractsstigmasterol
spellingShingle Malshani Nissanka
Manjula Weerasekera
Ayomi Dilhari
Ranga Dissanayake
Sajeewa Rathnayake
Gayan Wijesinghe
Phytomedicinal properties of Hygrophila schulli (Neeramulliya)
Iranian Journal of Basic Medical Sciences
alkaloids
anti-bacterial agents
anti-infective agents
anti-inflammatory agents
anti-oxidants
biodiversity
plant extracts
stigmasterol
title Phytomedicinal properties of Hygrophila schulli (Neeramulliya)
title_full Phytomedicinal properties of Hygrophila schulli (Neeramulliya)
title_fullStr Phytomedicinal properties of Hygrophila schulli (Neeramulliya)
title_full_unstemmed Phytomedicinal properties of Hygrophila schulli (Neeramulliya)
title_short Phytomedicinal properties of Hygrophila schulli (Neeramulliya)
title_sort phytomedicinal properties of hygrophila schulli neeramulliya
topic alkaloids
anti-bacterial agents
anti-infective agents
anti-inflammatory agents
anti-oxidants
biodiversity
plant extracts
stigmasterol
url https://ijbms.mums.ac.ir/article_22295_1a2ea94d316da57989ab62f9169afb2e.pdf
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