Fe-doped tricalcium phosphates: crystal structure and degradation behavior
β -tricalcium phosphate ( β -TCP, Ca3(PO4)2) is biodegradable ceramics with chemical and mineral compositions similar to those of bone. It is a potential candidate for bone repair surgery, and substituting the Fe ions can improve its biological behavior. In this study, we investigated the effect of...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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IOP Publishing
2020-01-01
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| Series: | Materials Research Express |
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| Online Access: | https://doi.org/10.1088/2053-1591/abcee8 |
| _version_ | 1797746803633815552 |
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| author | Kyung-Hyeon Yoo Hyeonjin Kim Woo Gyeong Sun Yong-Il Kim Seog-Young Yoon |
| author_facet | Kyung-Hyeon Yoo Hyeonjin Kim Woo Gyeong Sun Yong-Il Kim Seog-Young Yoon |
| author_sort | Kyung-Hyeon Yoo |
| collection | DOAJ |
| description | β -tricalcium phosphate ( β -TCP, Ca3(PO4)2) is biodegradable ceramics with chemical and mineral compositions similar to those of bone. It is a potential candidate for bone repair surgery, and substituting the Fe ions can improve its biological behavior. In this study, we investigated the effect of Fe ions on the structural deviation and in vitro behavior of β -TCP. Fe-doped β -TCP were synthesized by the co-precipitation method, and the heat treatment temperature was set at 1100 °C. The chemical state of the Fe-doped β -TCP was analyzed by x-ray photoelectron spectroscopy, while structural analysis was carried out by Rietveld refinement using the x-ray diffraction results. Fe ions existed in both Fe ^2+ and Fe ^3+ states and occupied the Ca-(4) and Ca-(5) sites. Fe ions enhanced the degradation of β -TCP and resorption behavior onto the surface of β -TCP during the immersion test. As a result, Fe ion improves the initial cell adhesion and proliferation behavior of β -TCP. |
| first_indexed | 2024-03-12T15:42:01Z |
| format | Article |
| id | doaj.art-4c3c1efcc4ae4c3dbd007a29179b4237 |
| institution | Directory Open Access Journal |
| issn | 2053-1591 |
| language | English |
| last_indexed | 2024-03-12T15:42:01Z |
| publishDate | 2020-01-01 |
| publisher | IOP Publishing |
| record_format | Article |
| series | Materials Research Express |
| spelling | doaj.art-4c3c1efcc4ae4c3dbd007a29179b42372023-08-09T15:54:42ZengIOP PublishingMaterials Research Express2053-15912020-01-0171212540310.1088/2053-1591/abcee8Fe-doped tricalcium phosphates: crystal structure and degradation behaviorKyung-Hyeon Yoo0https://orcid.org/0000-0001-5328-2919Hyeonjin Kim1Woo Gyeong Sun2Yong-Il Kim3Seog-Young Yoon4School of Materials Science and Engineering, Pusan National University , Busan, Republic of KoreaSchool of Materials Science and Engineering, Pusan National University , Busan, Republic of KoreaSchool of Materials Science and Engineering, Pusan National University , Busan, Republic of KoreaDepartment of Orthodontics, Dental Research Institute, Pusan National University , Yangsan 50612, Republic of KoreaSchool of Materials Science and Engineering, Pusan National University , Busan, Republic of Koreaβ -tricalcium phosphate ( β -TCP, Ca3(PO4)2) is biodegradable ceramics with chemical and mineral compositions similar to those of bone. It is a potential candidate for bone repair surgery, and substituting the Fe ions can improve its biological behavior. In this study, we investigated the effect of Fe ions on the structural deviation and in vitro behavior of β -TCP. Fe-doped β -TCP were synthesized by the co-precipitation method, and the heat treatment temperature was set at 1100 °C. The chemical state of the Fe-doped β -TCP was analyzed by x-ray photoelectron spectroscopy, while structural analysis was carried out by Rietveld refinement using the x-ray diffraction results. Fe ions existed in both Fe ^2+ and Fe ^3+ states and occupied the Ca-(4) and Ca-(5) sites. Fe ions enhanced the degradation of β -TCP and resorption behavior onto the surface of β -TCP during the immersion test. As a result, Fe ion improves the initial cell adhesion and proliferation behavior of β -TCP.https://doi.org/10.1088/2053-1591/abcee8iron-doped tricalcium phosphatecrystal structurein vitro behaviordegradationresorptioncell adhesion |
| spellingShingle | Kyung-Hyeon Yoo Hyeonjin Kim Woo Gyeong Sun Yong-Il Kim Seog-Young Yoon Fe-doped tricalcium phosphates: crystal structure and degradation behavior Materials Research Express iron-doped tricalcium phosphate crystal structure in vitro behavior degradation resorption cell adhesion |
| title | Fe-doped tricalcium phosphates: crystal structure and degradation behavior |
| title_full | Fe-doped tricalcium phosphates: crystal structure and degradation behavior |
| title_fullStr | Fe-doped tricalcium phosphates: crystal structure and degradation behavior |
| title_full_unstemmed | Fe-doped tricalcium phosphates: crystal structure and degradation behavior |
| title_short | Fe-doped tricalcium phosphates: crystal structure and degradation behavior |
| title_sort | fe doped tricalcium phosphates crystal structure and degradation behavior |
| topic | iron-doped tricalcium phosphate crystal structure in vitro behavior degradation resorption cell adhesion |
| url | https://doi.org/10.1088/2053-1591/abcee8 |
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