Gallbladder cancer in eastern India – The current scenario and the challenges for the future

Background: The incidence of gallbladder cancer is high in our institute. In India, there is lack of epidemiological study to identify putative risk factors causing gallbladder carcinoma. This study was designed to observe clinical, epidemiological aspects and risk factor of the gallbladder cancer....

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Main Authors: Mallick SK, Nahid G, Deb AR
Format: Article
Language:English
Published: KIMS Foundation and Research Center 2022-06-01
Series:Journal of Medical and Scientific Research
Subjects:
Online Access:http://jmsronline.com/archive-article/Gallbladder-cancer-in-eastern-India
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author Mallick SK
Nahid G
Deb AR
author_facet Mallick SK
Nahid G
Deb AR
author_sort Mallick SK
collection DOAJ
description Background: The incidence of gallbladder cancer is high in our institute. In India, there is lack of epidemiological study to identify putative risk factors causing gallbladder carcinoma. This study was designed to observe clinical, epidemiological aspects and risk factor of the gallbladder cancer. Early detection and diagnosis will help to decrease gallbladder carcinoma related mortality. Material and methods: After obtaining institutional ethics committee approval, gallbladder cases were identified from the institutional cancer registry. Then those data were tabulated in the excel sheet in the different epidemiological parameters and its outcome responses during June 2019 to December 2020. Results: Among 108 patients gallbladder adenocarcinoma were predominant (89.81%) followed by squamous cell carcinoma (10.19%). Most patients were female (64%) with metastatic presentation (86%). Most commonly encountered risk factors were Gall stone disease (59.26%). 11% patients with porcelain gallbladder causing gallbladder carcinoma were found in this study. Conclusion: The incidence has been on a steady rise in Indian population. The presentation is often with advanced disease and carries dismal prognosis. Most of the patient presented late, due to disease remain silent in early stage and also delayed and few were irregular in follow-up due to COVID-19 pandemic. Further studies with longer duration of follow-up are necessary.
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spelling doaj.art-4c4080260aa04919abe15613b1a52be72023-02-03T11:22:40ZengKIMS Foundation and Research CenterJournal of Medical and Scientific Research2321-13262394-112X2022-06-01102879210.17727/JMSR.2022/10-17Gallbladder cancer in eastern India – The current scenario and the challenges for the futureMallick SK0Nahid G1Deb AR2Department of Radiotherapy, Malda Medical College, West Bengal University of Health Science, West Bengal-700064, IndiaDepartment of Radiotherapy, North Bengal Medical College Kolkata, West Bengal University of Health Science, West Bengal-700064, IndiaDepartment of Radiotherapy, Medical College Kolkata, West Bengal University of Health Science, West Bengal-700064, IndiaBackground: The incidence of gallbladder cancer is high in our institute. In India, there is lack of epidemiological study to identify putative risk factors causing gallbladder carcinoma. This study was designed to observe clinical, epidemiological aspects and risk factor of the gallbladder cancer. Early detection and diagnosis will help to decrease gallbladder carcinoma related mortality. Material and methods: After obtaining institutional ethics committee approval, gallbladder cases were identified from the institutional cancer registry. Then those data were tabulated in the excel sheet in the different epidemiological parameters and its outcome responses during June 2019 to December 2020. Results: Among 108 patients gallbladder adenocarcinoma were predominant (89.81%) followed by squamous cell carcinoma (10.19%). Most patients were female (64%) with metastatic presentation (86%). Most commonly encountered risk factors were Gall stone disease (59.26%). 11% patients with porcelain gallbladder causing gallbladder carcinoma were found in this study. Conclusion: The incidence has been on a steady rise in Indian population. The presentation is often with advanced disease and carries dismal prognosis. Most of the patient presented late, due to disease remain silent in early stage and also delayed and few were irregular in follow-up due to COVID-19 pandemic. Further studies with longer duration of follow-up are necessary. http://jmsronline.com/archive-article/Gallbladder-cancer-in-eastern-Indiaincidencehepatitis b & c virusgallbladder cancergallbladder stone
spellingShingle Mallick SK
Nahid G
Deb AR
Gallbladder cancer in eastern India – The current scenario and the challenges for the future
Journal of Medical and Scientific Research
incidence
hepatitis b & c virus
gallbladder cancer
gallbladder stone
title Gallbladder cancer in eastern India – The current scenario and the challenges for the future
title_full Gallbladder cancer in eastern India – The current scenario and the challenges for the future
title_fullStr Gallbladder cancer in eastern India – The current scenario and the challenges for the future
title_full_unstemmed Gallbladder cancer in eastern India – The current scenario and the challenges for the future
title_short Gallbladder cancer in eastern India – The current scenario and the challenges for the future
title_sort gallbladder cancer in eastern india the current scenario and the challenges for the future
topic incidence
hepatitis b & c virus
gallbladder cancer
gallbladder stone
url http://jmsronline.com/archive-article/Gallbladder-cancer-in-eastern-India
work_keys_str_mv AT mallicksk gallbladdercancerineasternindiathecurrentscenarioandthechallengesforthefuture
AT nahidg gallbladdercancerineasternindiathecurrentscenarioandthechallengesforthefuture
AT debar gallbladdercancerineasternindiathecurrentscenarioandthechallengesforthefuture