Factors Influencing Atopic Dermatitis Incidence in Offspring
Atopic dermatitis (AD) is a chronic, recurrent skin condition resulting from both genetic and environmental factors. In recent decades, the prevalence of AD has increased considerably in some countries. However, given that the role of genetics is unlikely to have changed over this short period, the...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2019-08-01
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| Series: | Iranian Journal of Allergy, Asthma and Immunology |
| Subjects: | |
| Online Access: | https://ijaai.tums.ac.ir/index.php/ijaai/article/view/2095 |
| _version_ | 1811277677672267776 |
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| author | Siqi Ye Xiumei Mo Junfeng Liu Fenggen Yan Dacan Chen |
| author_facet | Siqi Ye Xiumei Mo Junfeng Liu Fenggen Yan Dacan Chen |
| author_sort | Siqi Ye |
| collection | DOAJ |
| description | Atopic dermatitis (AD) is a chronic, recurrent skin condition resulting from both genetic and environmental factors. In recent decades, the prevalence of AD has increased considerably in some countries. However, given that the role of genetics is unlikely to have changed over this short period, the increased prevalence is more likely to be explained by changes in environmental and maternal factors. The aim of this review is to comprehensively summarize the various factors impacting AD incidence in offspring and provide guidance for primary prevention. Recent research has demonstrated that environmental and climate factors, maternal history of allergies, gestational diabetes, and stress play essential roles in increasing the risk of AD in infants. Some factors have protective effects against the incidence of AD, including probiotic supplementation, fish intake, and moisturizers. This review also considers fundamental research into AD prevalence and factors that in the past were mistakenly thought to affect that prevalence, such as caesarean section and antigen avoidance. The potential influence of these factors on infant AD incidence remains inconclusive and needs further study. Furthermore, infants with a family history of atopic disease may benefit from early weaning or reduced breastfeeding duration. |
| first_indexed | 2024-04-13T00:20:01Z |
| format | Article |
| id | doaj.art-4c43adae4d274e6393ab623861658920 |
| institution | Directory Open Access Journal |
| issn | 1735-1502 1735-5249 |
| language | English |
| last_indexed | 2024-04-13T00:20:01Z |
| publishDate | 2019-08-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Allergy, Asthma and Immunology |
| spelling | doaj.art-4c43adae4d274e6393ab6238616589202022-12-22T03:10:47ZengTehran University of Medical SciencesIranian Journal of Allergy, Asthma and Immunology1735-15021735-52492019-08-0118410.18502/ijaai.v18i4.14132095Factors Influencing Atopic Dermatitis Incidence in OffspringSiqi Ye0Xiumei Mo1Junfeng Liu2Fenggen Yan3Dacan Chen4Department of Dermatology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, ChinaDepartment of Dermatology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, ChinaDepartment of Dermatology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, ChinaDepartment of Dermatology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, ChinaDepartment of Dermatology, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, ChinaAtopic dermatitis (AD) is a chronic, recurrent skin condition resulting from both genetic and environmental factors. In recent decades, the prevalence of AD has increased considerably in some countries. However, given that the role of genetics is unlikely to have changed over this short period, the increased prevalence is more likely to be explained by changes in environmental and maternal factors. The aim of this review is to comprehensively summarize the various factors impacting AD incidence in offspring and provide guidance for primary prevention. Recent research has demonstrated that environmental and climate factors, maternal history of allergies, gestational diabetes, and stress play essential roles in increasing the risk of AD in infants. Some factors have protective effects against the incidence of AD, including probiotic supplementation, fish intake, and moisturizers. This review also considers fundamental research into AD prevalence and factors that in the past were mistakenly thought to affect that prevalence, such as caesarean section and antigen avoidance. The potential influence of these factors on infant AD incidence remains inconclusive and needs further study. Furthermore, infants with a family history of atopic disease may benefit from early weaning or reduced breastfeeding duration.https://ijaai.tums.ac.ir/index.php/ijaai/article/view/2095Atopic dermatitisFactorsOffspringPrevalencePrimary prevention |
| spellingShingle | Siqi Ye Xiumei Mo Junfeng Liu Fenggen Yan Dacan Chen Factors Influencing Atopic Dermatitis Incidence in Offspring Iranian Journal of Allergy, Asthma and Immunology Atopic dermatitis Factors Offspring Prevalence Primary prevention |
| title | Factors Influencing Atopic Dermatitis Incidence in Offspring |
| title_full | Factors Influencing Atopic Dermatitis Incidence in Offspring |
| title_fullStr | Factors Influencing Atopic Dermatitis Incidence in Offspring |
| title_full_unstemmed | Factors Influencing Atopic Dermatitis Incidence in Offspring |
| title_short | Factors Influencing Atopic Dermatitis Incidence in Offspring |
| title_sort | factors influencing atopic dermatitis incidence in offspring |
| topic | Atopic dermatitis Factors Offspring Prevalence Primary prevention |
| url | https://ijaai.tums.ac.ir/index.php/ijaai/article/view/2095 |
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