Mini Review: Lactoferrin-binding protein of Streptococcus in Bovine Mastitis
Bovine mastitis is an udder inflammation mostly found in dairy cattle that causes enormous economic losses. Streptococcus is a bacterium that is often found in mastitis, including Streptococcus agalactiae, Streptococcus dysgalactiae, and Streptococcus uberis. These three species have lactoferrinbind...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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EDP Sciences
2022-01-01
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| Series: | BIO Web of Conferences |
| Online Access: | https://www.bio-conferences.org/articles/bioconf/pdf/2022/08/bioconf_isgp2022_01008.pdf |
| _version_ | 1811296930347614208 |
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| author | Iqomah Meta Arisona Alek Daru Prasetya Imawan Soedarmanto Adretta Yanuartono Indarjulianto Soedarmanto |
| author_facet | Iqomah Meta Arisona Alek Daru Prasetya Imawan Soedarmanto Adretta Yanuartono Indarjulianto Soedarmanto |
| author_sort | Iqomah Meta |
| collection | DOAJ |
| description | Bovine mastitis is an udder inflammation mostly found in dairy cattle that causes enormous economic losses. Streptococcus is a bacterium that is often found in mastitis, including Streptococcus agalactiae, Streptococcus dysgalactiae, and Streptococcus uberis. These three species have lactoferrinbinding protein (LBP) as one of their virulence factors. Lactoferrin is a host innate immune protein that acts as antibacterial, immunomodulator, anti-adhesion, and has iron-binding properties. The LBP on the surface of Streptococcus could bind to lactoferrin produced by host cells. Uniquely, the three Streptococcus bacteria showed different responses to lactoferrin. The lactoferrin-LBP bound on S. agalactiae and S. dysgalactiae was known to inhibit their penetration ability into the host epithelial cells, on the contrary, in S. uberis it could enhance their ability to invade the cells. This paper aims to review the role of the lactoferrin-binding protein of Streptococcus in bovine mastitis. |
| first_indexed | 2024-04-13T05:56:38Z |
| format | Article |
| id | doaj.art-4c43f5c9f53f457dbed92fb9d46d396d |
| institution | Directory Open Access Journal |
| issn | 2117-4458 |
| language | English |
| last_indexed | 2024-04-13T05:56:38Z |
| publishDate | 2022-01-01 |
| publisher | EDP Sciences |
| record_format | Article |
| series | BIO Web of Conferences |
| spelling | doaj.art-4c43f5c9f53f457dbed92fb9d46d396d2022-12-22T02:59:36ZengEDP SciencesBIO Web of Conferences2117-44582022-01-01490100810.1051/bioconf/20224901008bioconf_isgp2022_01008Mini Review: Lactoferrin-binding protein of Streptococcus in Bovine MastitisIqomah Meta0Arisona Alek1Daru Prasetya Imawan2Soedarmanto Adretta3Yanuartono4Indarjulianto Soedarmanto5Magister Sain Veteriner, Faculty of Veterinary Medicine, Universitas Gadjah MadaMagister Sain Veteriner, Faculty of Veterinary Medicine, Universitas Gadjah MadaMagister Sain Veteriner, Faculty of Veterinary Medicine, Universitas Gadjah MadaInternational Graduate of Veterinary Science and Technology Program, Faculty of Veterinary Science, Chulalongkorn UniversityDepartment of Internal Medicine, Faculty of Veterinary Medicine, Universitas Gadjah MadaDepartment of Internal Medicine, Faculty of Veterinary Medicine, Universitas Gadjah MadaBovine mastitis is an udder inflammation mostly found in dairy cattle that causes enormous economic losses. Streptococcus is a bacterium that is often found in mastitis, including Streptococcus agalactiae, Streptococcus dysgalactiae, and Streptococcus uberis. These three species have lactoferrinbinding protein (LBP) as one of their virulence factors. Lactoferrin is a host innate immune protein that acts as antibacterial, immunomodulator, anti-adhesion, and has iron-binding properties. The LBP on the surface of Streptococcus could bind to lactoferrin produced by host cells. Uniquely, the three Streptococcus bacteria showed different responses to lactoferrin. The lactoferrin-LBP bound on S. agalactiae and S. dysgalactiae was known to inhibit their penetration ability into the host epithelial cells, on the contrary, in S. uberis it could enhance their ability to invade the cells. This paper aims to review the role of the lactoferrin-binding protein of Streptococcus in bovine mastitis.https://www.bio-conferences.org/articles/bioconf/pdf/2022/08/bioconf_isgp2022_01008.pdf |
| spellingShingle | Iqomah Meta Arisona Alek Daru Prasetya Imawan Soedarmanto Adretta Yanuartono Indarjulianto Soedarmanto Mini Review: Lactoferrin-binding protein of Streptococcus in Bovine Mastitis BIO Web of Conferences |
| title | Mini Review: Lactoferrin-binding protein of Streptococcus in Bovine Mastitis |
| title_full | Mini Review: Lactoferrin-binding protein of Streptococcus in Bovine Mastitis |
| title_fullStr | Mini Review: Lactoferrin-binding protein of Streptococcus in Bovine Mastitis |
| title_full_unstemmed | Mini Review: Lactoferrin-binding protein of Streptococcus in Bovine Mastitis |
| title_short | Mini Review: Lactoferrin-binding protein of Streptococcus in Bovine Mastitis |
| title_sort | mini review lactoferrin binding protein of streptococcus in bovine mastitis |
| url | https://www.bio-conferences.org/articles/bioconf/pdf/2022/08/bioconf_isgp2022_01008.pdf |
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