Evaluation of next-generation sequencing versus next-generation flow cytometry for minimal-residual-disease detection in Chinese patients with multiple myeloma

Evaluation of next-generation sequencing versus next-generation flow cytometry for minimal-residual-disease detection in Chinese patients with multiple myeloma

Abstract Purpose To evaluate the efficacy of next-generation sequencing (NGS) in minimal-residual-disease (MRD) monitoring in Chinese patients with multiple myeloma (MM). Methods This study analyzed 60 Chinese MM patients. During MRD monitoring in these patients’ post-therapy, clonal immunoglobulin...

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Bibliographic Details
Main Authors: Mo Zhou, Yan Chen, Yanlei Gong, Mingqing Zhu, Jiannong Cen, Jinlan Pan, Lingzhi Yan, Jingjing Shang, Song Jin, Xiaolan Shi, Weiqin Yao, Shuang Yan, Depei Wu, Suning Chen, Chengcheng Fu, Li Yao
Format: Article
Language:English
Published: Springer 2024-03-01
Series:Discover Oncology
Subjects:
Multiple myeloma
Minimal residual disease
Next-generation sequencing
IGH gene rearrangement
Next-generation flow cytometry
Online Access:https://doi.org/10.1007/s12672-024-00938-w

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