The chromatin-associated lncREST ensures effective replication stress response by promoting the assembly of fork signaling factors
ABSTRACT Besides the well-characterized protein network involved in the replication stress response, several regulatory RNAs have been shown to play a role in this critical process. However, it has remained elusive whether they act locally at the stressed forks. Here, by investigating the RNAs local...
Main Authors: | Luisa Statello, José Miguel Fernandez-Justel, Jovanna González, Marta Montes, Alessia Ranieri, Enrique Goñi, Aina M. Mas, Maite Huarte |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-02-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-024-45183-5 |
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