Adult stem cells therapy for the heart
Acute myocardial infarction causes irreversible loss of cardiomyocytes and endothelial cells compromising the cardiac function of patients. For some patients, current therapeutic approaches are not sufficient to prevent myocardial remodeling, which aggravates the disease. The potential of many types...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Instituto Israelita de Ensino e Pesquisa Albert Einstein
2009-03-01
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| Series: | Einstein (São Paulo) |
| Subjects: | |
| Online Access: | http://apps.einstein.br/revista/arquivos/PDF/920-Einsteinv7n2p229-36_ing.pdf |
| _version_ | 1818344498917277696 |
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| author | Daniela Mara Oliveira Alexandre Holthausen Campos |
| author_facet | Daniela Mara Oliveira Alexandre Holthausen Campos |
| author_sort | Daniela Mara Oliveira |
| collection | DOAJ |
| description | Acute myocardial infarction causes irreversible loss of cardiomyocytes and endothelial cells compromising the cardiac function of patients. For some patients, current therapeutic approaches are not sufficient to prevent myocardial remodeling, which aggravates the disease. The potential of many types of adult bone marrow-derived progenitor cells in replacing damaged myocardium with functional cells has been investigated in several clinical and experimental studies. It has been demonstrated that these cells have an overall beneficial effect on heart function although the mechanism or multiple mechanisms involved have not been elucidated yet. Here, it will be reviewed some aspects of this fast-growing and controversial field of adult autologous progenitor/stem cells for cardiac repair. |
| first_indexed | 2024-12-13T16:47:26Z |
| format | Article |
| id | doaj.art-4c4c1e9ada92448bb7a2b016b9115d0b |
| institution | Directory Open Access Journal |
| issn | 1679-4508 |
| language | English |
| last_indexed | 2024-12-13T16:47:26Z |
| publishDate | 2009-03-01 |
| publisher | Instituto Israelita de Ensino e Pesquisa Albert Einstein |
| record_format | Article |
| series | Einstein (São Paulo) |
| spelling | doaj.art-4c4c1e9ada92448bb7a2b016b9115d0b2022-12-21T23:38:07ZengInstituto Israelita de Ensino e Pesquisa Albert EinsteinEinstein (São Paulo)1679-45082009-03-0172229236Adult stem cells therapy for the heartDaniela Mara OliveiraAlexandre Holthausen CamposAcute myocardial infarction causes irreversible loss of cardiomyocytes and endothelial cells compromising the cardiac function of patients. For some patients, current therapeutic approaches are not sufficient to prevent myocardial remodeling, which aggravates the disease. The potential of many types of adult bone marrow-derived progenitor cells in replacing damaged myocardium with functional cells has been investigated in several clinical and experimental studies. It has been demonstrated that these cells have an overall beneficial effect on heart function although the mechanism or multiple mechanisms involved have not been elucidated yet. Here, it will be reviewed some aspects of this fast-growing and controversial field of adult autologous progenitor/stem cells for cardiac repair.http://apps.einstein.br/revista/arquivos/PDF/920-Einsteinv7n2p229-36_ing.pdfStem cellsHeartMyocardial infarction |
| spellingShingle | Daniela Mara Oliveira Alexandre Holthausen Campos Adult stem cells therapy for the heart Einstein (São Paulo) Stem cells Heart Myocardial infarction |
| title | Adult stem cells therapy for the heart |
| title_full | Adult stem cells therapy for the heart |
| title_fullStr | Adult stem cells therapy for the heart |
| title_full_unstemmed | Adult stem cells therapy for the heart |
| title_short | Adult stem cells therapy for the heart |
| title_sort | adult stem cells therapy for the heart |
| topic | Stem cells Heart Myocardial infarction |
| url | http://apps.einstein.br/revista/arquivos/PDF/920-Einsteinv7n2p229-36_ing.pdf |
| work_keys_str_mv | AT danielamaraoliveira adultstemcellstherapyfortheheart AT alexandreholthausencampos adultstemcellstherapyfortheheart |