Novel Insights into the Protective Properties of ACTH<sub>(4-7)</sub>PGP (Semax) Peptide at the Transcriptome Level Following Cerebral Ischaemia–Reperfusion in Rats

Novel Insights into the Protective Properties of ACTH<sub>(4-7)</sub>PGP (Semax) Peptide at the Transcriptome Level Following Cerebral Ischaemia–Reperfusion in Rats

Cerebral ischaemia is the most common cause of impaired brain function. Biologically active peptides represent potential drugs for reducing the damage that occurs after ischaemia. The synthetic melanocortin derivative, ACTH<sub>(4-7)</sub>PGP (Semax), has been used successfully in the tr...

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Bibliographic Details
Main Authors: Ivan B. Filippenkov, Vasily V. Stavchansky, Alina E. Denisova, Vadim V. Yuzhakov, Larisa E. Sevan’kaeva, Olga Y. Sudarkina, Veronika G. Dmitrieva, Leonid V. Gubsky, Nikolai F. Myasoedov, Svetlana A. Limborska, Lyudmila V. Dergunova
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Genes
Subjects:
tMCAO
mRNA expression
RNA-Seq
synthetic melanocortin derivative ACTH<sub>(4-7)</sub>PGP (Semax)
peptide regulation
Online Access:https://www.mdpi.com/2073-4425/11/6/681

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