Efficacy and safety of trabeculectomy at the inferior limbus for patients of intraocular pressure after failed glaucoma filtration
AIM: To evaluate the efficacy and safety of trabeculectomy at the inferior limbus for patients of intraocular pressure(IOP)after failed glaucoma filtration.METHODS: A retrospective analysis was conducted to identify 51 glaucoma patients with 61 eyes that had undergone trabeculectomy at the inferior...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Press of International Journal of Ophthalmology (IJO PRESS)
2022-09-01
|
| Series: | Guoji Yanke Zazhi |
| Subjects: | |
| Online Access: | http://ies.ijo.cn/cn_publish/2022/9/202209026.pdf |
| _version_ | 1811187644236824576 |
|---|---|
| author | Qian Ye Yan-Ping Song Xiao Chen Wen-Qiang Zhang |
| author_facet | Qian Ye Yan-Ping Song Xiao Chen Wen-Qiang Zhang |
| author_sort | Qian Ye |
| collection | DOAJ |
| description | AIM: To evaluate the efficacy and safety of trabeculectomy at the inferior limbus for patients of intraocular pressure(IOP)after failed glaucoma filtration.METHODS: A retrospective analysis was conducted to identify 51 glaucoma patients with 61 eyes that had undergone trabeculectomy at the inferior limbus for patients of IOP after failed glaucoma filtration. The preoperative and postoperative IOP, visual acuity and number of IOP-lowering drugs, as well as intraoperative and postoperative complications were extracted. Surgical success rates were calculated using Kaplan-Meier survival analysis.RESULTS: The postoperative follow-up time ranged from 6-76(mean 30.15±14.10)mo. The preoperative IOP of 61 eyes was 35.98±10.01mmHg, the IOP after the surgery at 1wk, 1, 3, 6mo, 1a and the IOP of last follow-up visit were 9.62±4.90, 13.15±4.51, 16.05±7.37, 16.48±6.81, 16.68±6.42, 16.77±7.56 mmHg respectively, all of these were different compared to the preoperative IOP(P<0.001). The postoperative complete success rates at 6mo, 1 and 2a were 62%, 49% and 36%, respectively and the partial success rates were 93%, 85% and 81%, respectively. There were 34 eyes(56%)formed functional filtration blebs. There were 3.33±0.77 kinds of IOP-lowering eye drops used before surgery, and it was decreased to 1.41±1.44 kinds of eye drops(t=9.86, P<0.001)at 3mo after surgery. There was no severe complication observed such as filtering bleb infection and endophthalmitis.CONCLUSION: Trabeculectomy at the inferior limbus offers the opportunity for patients with uncontrolled IOP after failed glaucoma filtration, and it can still be used as a safe and effective treatment for patients, although it is relatively difficult to operate. |
| first_indexed | 2024-04-11T14:05:45Z |
| format | Article |
| id | doaj.art-4c4cf5273cb141508c0123d8544f18d3 |
| institution | Directory Open Access Journal |
| issn | 1672-5123 |
| language | English |
| last_indexed | 2024-04-11T14:05:45Z |
| publishDate | 2022-09-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | Guoji Yanke Zazhi |
| spelling | doaj.art-4c4cf5273cb141508c0123d8544f18d32022-12-22T04:19:53ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51232022-09-012291550155310.3980/j.issn.1672-5123.2022.9.26202209026Efficacy and safety of trabeculectomy at the inferior limbus for patients of intraocular pressure after failed glaucoma filtrationQian Ye0Yan-Ping Song1Xiao Chen2Wen-Qiang Zhang3Department of Ophthalmology, the Central Theater General Hospital of PLA;Fundus Laser Clinical Medicine Research Center, Wuhan 430070, Hubei Province, ChinaDepartment of Ophthalmology, the Central Theater General Hospital of PLA;Fundus Laser Clinical Medicine Research Center, Wuhan 430070, Hubei Province, ChinaDepartment of Ophthalmology, the Central Theater General Hospital of PLA;Fundus Laser Clinical Medicine Research Center, Wuhan 430070, Hubei Province, ChinaDepartment of Ophthalmology, the Central Theater General Hospital of PLA;Fundus Laser Clinical Medicine Research Center, Wuhan 430070, Hubei Province, ChinaAIM: To evaluate the efficacy and safety of trabeculectomy at the inferior limbus for patients of intraocular pressure(IOP)after failed glaucoma filtration.METHODS: A retrospective analysis was conducted to identify 51 glaucoma patients with 61 eyes that had undergone trabeculectomy at the inferior limbus for patients of IOP after failed glaucoma filtration. The preoperative and postoperative IOP, visual acuity and number of IOP-lowering drugs, as well as intraoperative and postoperative complications were extracted. Surgical success rates were calculated using Kaplan-Meier survival analysis.RESULTS: The postoperative follow-up time ranged from 6-76(mean 30.15±14.10)mo. The preoperative IOP of 61 eyes was 35.98±10.01mmHg, the IOP after the surgery at 1wk, 1, 3, 6mo, 1a and the IOP of last follow-up visit were 9.62±4.90, 13.15±4.51, 16.05±7.37, 16.48±6.81, 16.68±6.42, 16.77±7.56 mmHg respectively, all of these were different compared to the preoperative IOP(P<0.001). The postoperative complete success rates at 6mo, 1 and 2a were 62%, 49% and 36%, respectively and the partial success rates were 93%, 85% and 81%, respectively. There were 34 eyes(56%)formed functional filtration blebs. There were 3.33±0.77 kinds of IOP-lowering eye drops used before surgery, and it was decreased to 1.41±1.44 kinds of eye drops(t=9.86, P<0.001)at 3mo after surgery. There was no severe complication observed such as filtering bleb infection and endophthalmitis.CONCLUSION: Trabeculectomy at the inferior limbus offers the opportunity for patients with uncontrolled IOP after failed glaucoma filtration, and it can still be used as a safe and effective treatment for patients, although it is relatively difficult to operate.http://ies.ijo.cn/cn_publish/2022/9/202209026.pdftrabeculectomy at the inferior limbusglaucoma filtrationuncontrolled intraocular pressure |
| spellingShingle | Qian Ye Yan-Ping Song Xiao Chen Wen-Qiang Zhang Efficacy and safety of trabeculectomy at the inferior limbus for patients of intraocular pressure after failed glaucoma filtration Guoji Yanke Zazhi trabeculectomy at the inferior limbus glaucoma filtration uncontrolled intraocular pressure |
| title | Efficacy and safety of trabeculectomy at the inferior limbus for patients of intraocular pressure after failed glaucoma filtration |
| title_full | Efficacy and safety of trabeculectomy at the inferior limbus for patients of intraocular pressure after failed glaucoma filtration |
| title_fullStr | Efficacy and safety of trabeculectomy at the inferior limbus for patients of intraocular pressure after failed glaucoma filtration |
| title_full_unstemmed | Efficacy and safety of trabeculectomy at the inferior limbus for patients of intraocular pressure after failed glaucoma filtration |
| title_short | Efficacy and safety of trabeculectomy at the inferior limbus for patients of intraocular pressure after failed glaucoma filtration |
| title_sort | efficacy and safety of trabeculectomy at the inferior limbus for patients of intraocular pressure after failed glaucoma filtration |
| topic | trabeculectomy at the inferior limbus glaucoma filtration uncontrolled intraocular pressure |
| url | http://ies.ijo.cn/cn_publish/2022/9/202209026.pdf |
| work_keys_str_mv | AT qianye efficacyandsafetyoftrabeculectomyattheinferiorlimbusforpatientsofintraocularpressureafterfailedglaucomafiltration AT yanpingsong efficacyandsafetyoftrabeculectomyattheinferiorlimbusforpatientsofintraocularpressureafterfailedglaucomafiltration AT xiaochen efficacyandsafetyoftrabeculectomyattheinferiorlimbusforpatientsofintraocularpressureafterfailedglaucomafiltration AT wenqiangzhang efficacyandsafetyoftrabeculectomyattheinferiorlimbusforpatientsofintraocularpressureafterfailedglaucomafiltration |