Supplement of microbiota-accessible carbohydrates prevents neuroinflammation and cognitive decline by improving the gut microbiota-brain axis in diet-induced obese mice

Supplement of microbiota-accessible carbohydrates prevents neuroinflammation and cognitive decline by improving the gut microbiota-brain axis in diet-induced obese mice

Abstract Background Western pattern diets induce neuroinflammation and impair cognitive behavior in humans and animals. Neuroinflammation and cognitive impairment have been associated with microbiota dysbiosis, through the gut-brain axis. Furthermore, microbiota-accessible carbohydrates (MACs) found...

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Bibliographic Details
Main Authors: Hongli Shi, Qiao Wang, Mingxuan Zheng, Shanshan Hao, Jeremy S. Lum, Xi Chen, Xu-Feng Huang, Yinghua Yu, Kuiyang Zheng
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Journal of Neuroinflammation
Subjects:
Microbiota-accessible carbohydrate
Obesity
Cognition
Gut microbiota
Gut-brain axis
Online Access:http://link.springer.com/article/10.1186/s12974-020-01760-1

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