Clinical Outcomes of Lung Transplantation: Experience at Asan Medical Center
Background: Lung transplantation is a life-saving procedure in patients with end-stage lung disease, and is increasingly performed in Korea. Methods: We retrospectively evaluated the outcomes of patients who received a lung transplant at Asan Medical Center between January 2008 and December 2016....
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Korean Society for Thoracic and Cardiovascular Surgery
2018-02-01
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| Series: | Korean Journal of Thoracic and Cardiovascular Surgery |
| Subjects: | |
| Online Access: | http://www.kjtcvs.org/journal/download_pdf.php?doi=10.5090/kjtcs.2018.51.1.22 |
| _version_ | 1818414419636387840 |
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| author | Yong Ho Jeong Sehoon Choi Seung-Il Park Dong Kwan Kim Asan Medical Center Lung Transplantation Team |
| author_facet | Yong Ho Jeong Sehoon Choi Seung-Il Park Dong Kwan Kim Asan Medical Center Lung Transplantation Team |
| author_sort | Yong Ho Jeong |
| collection | DOAJ |
| description | Background: Lung transplantation is a life-saving procedure in patients with end-stage lung disease, and is
increasingly performed in Korea. Methods: We retrospectively evaluated the outcomes of patients who received
a lung transplant at Asan Medical Center between January 2008 and December 2016. Thirteen of 54
patients experienced multiorgan transplantation; the remaining 41 who received only lung grafts were
included. Results: The mean age of the lung transplant recipients was 44.6 years; 27 were men and 14 were
women. The most frequent reasons were idiopathic interstitial pneumonia (21 of 41 patients, 51.2%), interstitial
lung disease (9 of 41, 22.0%), and bronchiolitis obliterans after bone marrow transplantation (7 of 41,
17.1%). The median waiting time was 47 days, and many patients received preoperative intensive care (27
of 41, 65.9%), ventilator support (26 of 41, 63.4%), or extracorporeal life support (19 of 41, 46.3%). All 41
patients received bilateral lung grafts. Ten deaths occurred (24.3%), including 5 cases of early mortality
(12.2%) and 5 cases of late mortality (12.2%). The 1-, 3-, and 5-year survival rates were 78.9%, 74.2%, and
69.3%, respectively. Conclusion: Despite a high percentage of patients who required preoperative intensive
care, the transplantation outcomes were acceptable. |
| first_indexed | 2024-12-14T11:18:48Z |
| format | Article |
| id | doaj.art-4c4fc867cafc41298d74e66cc98ba82e |
| institution | Directory Open Access Journal |
| issn | 2233-601X 2093-6516 |
| language | English |
| last_indexed | 2024-12-14T11:18:48Z |
| publishDate | 2018-02-01 |
| publisher | Korean Society for Thoracic and Cardiovascular Surgery |
| record_format | Article |
| series | Korean Journal of Thoracic and Cardiovascular Surgery |
| spelling | doaj.art-4c4fc867cafc41298d74e66cc98ba82e2022-12-21T23:03:51ZengKorean Society for Thoracic and Cardiovascular SurgeryKorean Journal of Thoracic and Cardiovascular Surgery2233-601X2093-65162018-02-01511222810.5090/kjtcs.2018.51.1.22Clinical Outcomes of Lung Transplantation: Experience at Asan Medical CenterYong Ho Jeong0Sehoon Choi1Seung-Il Park2Dong Kwan Kim3Asan Medical Center Lung Transplantation Team4Asan Medical CenterAsan Medical CenterAsan Medical CenterAsan Medical CenterAsan Medical CenterBackground: Lung transplantation is a life-saving procedure in patients with end-stage lung disease, and is increasingly performed in Korea. Methods: We retrospectively evaluated the outcomes of patients who received a lung transplant at Asan Medical Center between January 2008 and December 2016. Thirteen of 54 patients experienced multiorgan transplantation; the remaining 41 who received only lung grafts were included. Results: The mean age of the lung transplant recipients was 44.6 years; 27 were men and 14 were women. The most frequent reasons were idiopathic interstitial pneumonia (21 of 41 patients, 51.2%), interstitial lung disease (9 of 41, 22.0%), and bronchiolitis obliterans after bone marrow transplantation (7 of 41, 17.1%). The median waiting time was 47 days, and many patients received preoperative intensive care (27 of 41, 65.9%), ventilator support (26 of 41, 63.4%), or extracorporeal life support (19 of 41, 46.3%). All 41 patients received bilateral lung grafts. Ten deaths occurred (24.3%), including 5 cases of early mortality (12.2%) and 5 cases of late mortality (12.2%). The 1-, 3-, and 5-year survival rates were 78.9%, 74.2%, and 69.3%, respectively. Conclusion: Despite a high percentage of patients who required preoperative intensive care, the transplantation outcomes were acceptable.http://www.kjtcvs.org/journal/download_pdf.php?doi=10.5090/kjtcs.2018.51.1.22Lung transplantationExtracorporeal membrane oxygenation (ECMO)Survival |
| spellingShingle | Yong Ho Jeong Sehoon Choi Seung-Il Park Dong Kwan Kim Asan Medical Center Lung Transplantation Team Clinical Outcomes of Lung Transplantation: Experience at Asan Medical Center Korean Journal of Thoracic and Cardiovascular Surgery Lung transplantation Extracorporeal membrane oxygenation (ECMO) Survival |
| title | Clinical Outcomes of Lung Transplantation: Experience at Asan Medical Center |
| title_full | Clinical Outcomes of Lung Transplantation: Experience at Asan Medical Center |
| title_fullStr | Clinical Outcomes of Lung Transplantation: Experience at Asan Medical Center |
| title_full_unstemmed | Clinical Outcomes of Lung Transplantation: Experience at Asan Medical Center |
| title_short | Clinical Outcomes of Lung Transplantation: Experience at Asan Medical Center |
| title_sort | clinical outcomes of lung transplantation experience at asan medical center |
| topic | Lung transplantation Extracorporeal membrane oxygenation (ECMO) Survival |
| url | http://www.kjtcvs.org/journal/download_pdf.php?doi=10.5090/kjtcs.2018.51.1.22 |
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