TRPV4 channel inhibits TGF-β1-induced proliferation of hepatic stellate cells.

TRPV4 channel inhibits TGF-β1-induced proliferation of hepatic stellate cells.

TRPV4, one of the TRP channels, is implicated in diverse physiological and pathological processes including cell proliferation. However, the role of TRPV4 in liver fibrosis is largely unknown. Here, we characterized the role of TRPV4 in regulating HSC-T6 cell proliferation. TRPV4 mRNA and protein we...

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Bibliographic Details
Main Authors: Yang Song, Lei Zhan, Mingzhe Yu, Cheng Huang, Xiaoming Meng, Taotao Ma, Lei Zhang, Jun Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4094468?pdf=render

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