A circuitous route for in vitro multi-enzyme cascade production of cytidine triphosphate to overcome the thermodynamic bottleneck

Abstract Cytidine triphosphate (CTP), as a substance involved in the metabolism of phospholipids, proteins and nucleic acids, has precise drug effects and is a direct precursor for the synthesis of drugs such as citicoline. In this study, we established an in vitro six-enzyme cascade system to gener...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Zonglin Li, Yahui Zhong, Zhoulei Qing, Zhimin Li
التنسيق: مقال
اللغة:English
منشور في: SpringerOpen 2024-01-01
سلاسل:Bioresources and Bioprocessing
الموضوعات:
الوصول للمادة أونلاين:https://doi.org/10.1186/s40643-023-00724-6