A circuitous route for in vitro multi-enzyme cascade production of cytidine triphosphate to overcome the thermodynamic bottleneck

Abstract Cytidine triphosphate (CTP), as a substance involved in the metabolism of phospholipids, proteins and nucleic acids, has precise drug effects and is a direct precursor for the synthesis of drugs such as citicoline. In this study, we established an in vitro six-enzyme cascade system to gener...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Zonglin Li, Yahui Zhong, Zhoulei Qing, Zhimin Li
स्वरूप: लेख
भाषा:English
प्रकाशित: SpringerOpen 2024-01-01
श्रृंखला:Bioresources and Bioprocessing
विषय:
ऑनलाइन पहुंच:https://doi.org/10.1186/s40643-023-00724-6