Differential gene expression identifies a transcriptional regulatory network involving ER-alpha and PITX1 in invasive epithelial ovarian cancer

Differential gene expression identifies a transcriptional regulatory network involving ER-alpha and PITX1 in invasive epithelial ovarian cancer

Abstract Background The heterogeneous subtypes and stages of epithelial ovarian cancer (EOC) differ in their biological features, invasiveness, and response to chemotherapy, but the transcriptional regulators causing their differences remain nebulous. Methods In this study, we compared high-grade se...

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Bibliographic Details
Main Authors: Yichao Li, Sushil K. Jaiswal, Rupleen Kaur, Dana Alsaadi, Xiaoyu Liang, Frank Drews, Julie A. DeLoia, Thomas Krivak, Hanna M. Petrykowska, Valer Gotea, Lonnie Welch, Laura Elnitski
Format: Article
Language:English
Published: BMC 2021-07-01
Series:BMC Cancer
Subjects:
High-grade serous ovarian cancer
HGSOC
Serous borderline tumor
SBT
PITX1
Estrogen receptor-alpha
Online Access:https://doi.org/10.1186/s12885-021-08276-8

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