Malignant melanoma presenting as an isolated pleural effusion
Isolated pleural effusion is a very rare presentation of malignant melanoma. A 46 year-old male patient presented to us with complaints of shortness of breath during the previous month. A contrast enhanced computed tomography (CECT) imaging scan of his thorax showed right-sided pleural effusion with...
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PAGEPress Publications
2015-12-01
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Series: | Monaldi Archives for Chest Disease |
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Online Access: | https://www.monaldi-archives.org/index.php/macd/article/view/228 |
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author | M. Shameem J. Akhtar U. Baneen N. Ahmad Khan R. Bhargava Z. Ahmed M. Shahid M. Azfar Siddiqui |
author_facet | M. Shameem J. Akhtar U. Baneen N. Ahmad Khan R. Bhargava Z. Ahmed M. Shahid M. Azfar Siddiqui |
author_sort | M. Shameem |
collection | DOAJ |
description | Isolated pleural effusion is a very rare presentation of malignant melanoma. A 46 year-old male patient presented to us with complaints of shortness of breath during the previous month. A contrast enhanced computed tomography (CECT) imaging scan of his thorax showed right-sided pleural effusion with the absence of any mass lesion or mediastinal lymphadenopathy. Cytology of his pleural fluid showed pigmented cells suggestive of malignant melanoma. Staining of the pleural fluid cells with immunohistological markers for melanoma (HMB 45 and S 100) were positive. An examination of his skin did not reveal any pigmented lesion, nor was there a past history of malignant melanoma for this patient. The patient responded well to therapy for malignant melanoma and has remained asymptomatic for the last year. This patient was diagnosed with a rare case of primary malignant melanoma of the pleura presenting as isolated pleural effusion. |
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format | Article |
id | doaj.art-4c571acec05449f0ab7a24d66d44fc51 |
institution | Directory Open Access Journal |
issn | 1122-0643 2532-5264 |
language | English |
last_indexed | 2024-12-12T10:42:20Z |
publishDate | 2015-12-01 |
publisher | PAGEPress Publications |
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series | Monaldi Archives for Chest Disease |
spelling | doaj.art-4c571acec05449f0ab7a24d66d44fc512022-12-22T00:27:00ZengPAGEPress PublicationsMonaldi Archives for Chest Disease1122-06432532-52642015-12-0175210.4081/monaldi.2011.228Malignant melanoma presenting as an isolated pleural effusionM. Shameem0J. Akhtar1U. Baneen2N. Ahmad Khan3R. Bhargava4Z. Ahmed5M. Shahid6M. Azfar Siddiqui7Department of Tuberculosis and Chest Disease, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh 202002, UPDepartment of Tuberculosis and Chest Disease, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh 202002, UPDepartment of Tuberculosis and Chest Disease, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh 202002, UPDepartment of Tuberculosis and Chest Disease, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh 202002, UPDepartment of Tuberculosis and Chest Disease, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh 202002, UPDepartment of Tuberculosis and Chest Disease, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh 202002, UPDepartment of Tuberculosis and Chest Disease, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh 202002, UPDepartment of Radiology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh 202002, UPIsolated pleural effusion is a very rare presentation of malignant melanoma. A 46 year-old male patient presented to us with complaints of shortness of breath during the previous month. A contrast enhanced computed tomography (CECT) imaging scan of his thorax showed right-sided pleural effusion with the absence of any mass lesion or mediastinal lymphadenopathy. Cytology of his pleural fluid showed pigmented cells suggestive of malignant melanoma. Staining of the pleural fluid cells with immunohistological markers for melanoma (HMB 45 and S 100) were positive. An examination of his skin did not reveal any pigmented lesion, nor was there a past history of malignant melanoma for this patient. The patient responded well to therapy for malignant melanoma and has remained asymptomatic for the last year. This patient was diagnosed with a rare case of primary malignant melanoma of the pleura presenting as isolated pleural effusion.https://www.monaldi-archives.org/index.php/macd/article/view/228Malignant melanomaPleuraIsolated pleural effusion |
spellingShingle | M. Shameem J. Akhtar U. Baneen N. Ahmad Khan R. Bhargava Z. Ahmed M. Shahid M. Azfar Siddiqui Malignant melanoma presenting as an isolated pleural effusion Monaldi Archives for Chest Disease Malignant melanoma Pleura Isolated pleural effusion |
title | Malignant melanoma presenting as an isolated pleural effusion |
title_full | Malignant melanoma presenting as an isolated pleural effusion |
title_fullStr | Malignant melanoma presenting as an isolated pleural effusion |
title_full_unstemmed | Malignant melanoma presenting as an isolated pleural effusion |
title_short | Malignant melanoma presenting as an isolated pleural effusion |
title_sort | malignant melanoma presenting as an isolated pleural effusion |
topic | Malignant melanoma Pleura Isolated pleural effusion |
url | https://www.monaldi-archives.org/index.php/macd/article/view/228 |
work_keys_str_mv | AT mshameem malignantmelanomapresentingasanisolatedpleuraleffusion AT jakhtar malignantmelanomapresentingasanisolatedpleuraleffusion AT ubaneen malignantmelanomapresentingasanisolatedpleuraleffusion AT nahmadkhan malignantmelanomapresentingasanisolatedpleuraleffusion AT rbhargava malignantmelanomapresentingasanisolatedpleuraleffusion AT zahmed malignantmelanomapresentingasanisolatedpleuraleffusion AT mshahid malignantmelanomapresentingasanisolatedpleuraleffusion AT mazfarsiddiqui malignantmelanomapresentingasanisolatedpleuraleffusion |