Malignant melanoma presenting as an isolated pleural effusion

Isolated pleural effusion is a very rare presentation of malignant melanoma. A 46 year-old male patient presented to us with complaints of shortness of breath during the previous month. A contrast enhanced computed tomography (CECT) imaging scan of his thorax showed right-sided pleural effusion with...

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Main Authors: M. Shameem, J. Akhtar, U. Baneen, N. Ahmad Khan, R. Bhargava, Z. Ahmed, M. Shahid, M. Azfar Siddiqui
Format: Article
Language:English
Published: PAGEPress Publications 2015-12-01
Series:Monaldi Archives for Chest Disease
Subjects:
Online Access:https://www.monaldi-archives.org/index.php/macd/article/view/228
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author M. Shameem
J. Akhtar
U. Baneen
N. Ahmad Khan
R. Bhargava
Z. Ahmed
M. Shahid
M. Azfar Siddiqui
author_facet M. Shameem
J. Akhtar
U. Baneen
N. Ahmad Khan
R. Bhargava
Z. Ahmed
M. Shahid
M. Azfar Siddiqui
author_sort M. Shameem
collection DOAJ
description Isolated pleural effusion is a very rare presentation of malignant melanoma. A 46 year-old male patient presented to us with complaints of shortness of breath during the previous month. A contrast enhanced computed tomography (CECT) imaging scan of his thorax showed right-sided pleural effusion with the absence of any mass lesion or mediastinal lymphadenopathy. Cytology of his pleural fluid showed pigmented cells suggestive of malignant melanoma. Staining of the pleural fluid cells with immunohistological markers for melanoma (HMB 45 and S 100) were positive. An examination of his skin did not reveal any pigmented lesion, nor was there a past history of malignant melanoma for this patient. The patient responded well to therapy for malignant melanoma and has remained asymptomatic for the last year. This patient was diagnosed with a rare case of primary malignant melanoma of the pleura presenting as isolated pleural effusion.
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spelling doaj.art-4c571acec05449f0ab7a24d66d44fc512022-12-22T00:27:00ZengPAGEPress PublicationsMonaldi Archives for Chest Disease1122-06432532-52642015-12-0175210.4081/monaldi.2011.228Malignant melanoma presenting as an isolated pleural effusionM. Shameem0J. Akhtar1U. Baneen2N. Ahmad Khan3R. Bhargava4Z. Ahmed5M. Shahid6M. Azfar Siddiqui7Department of Tuberculosis and Chest Disease, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh 202002, UPDepartment of Tuberculosis and Chest Disease, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh 202002, UPDepartment of Tuberculosis and Chest Disease, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh 202002, UPDepartment of Tuberculosis and Chest Disease, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh 202002, UPDepartment of Tuberculosis and Chest Disease, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh 202002, UPDepartment of Tuberculosis and Chest Disease, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh 202002, UPDepartment of Tuberculosis and Chest Disease, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh 202002, UPDepartment of Radiology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh 202002, UPIsolated pleural effusion is a very rare presentation of malignant melanoma. A 46 year-old male patient presented to us with complaints of shortness of breath during the previous month. A contrast enhanced computed tomography (CECT) imaging scan of his thorax showed right-sided pleural effusion with the absence of any mass lesion or mediastinal lymphadenopathy. Cytology of his pleural fluid showed pigmented cells suggestive of malignant melanoma. Staining of the pleural fluid cells with immunohistological markers for melanoma (HMB 45 and S 100) were positive. An examination of his skin did not reveal any pigmented lesion, nor was there a past history of malignant melanoma for this patient. The patient responded well to therapy for malignant melanoma and has remained asymptomatic for the last year. This patient was diagnosed with a rare case of primary malignant melanoma of the pleura presenting as isolated pleural effusion.https://www.monaldi-archives.org/index.php/macd/article/view/228Malignant melanomaPleuraIsolated pleural effusion
spellingShingle M. Shameem
J. Akhtar
U. Baneen
N. Ahmad Khan
R. Bhargava
Z. Ahmed
M. Shahid
M. Azfar Siddiqui
Malignant melanoma presenting as an isolated pleural effusion
Monaldi Archives for Chest Disease
Malignant melanoma
Pleura
Isolated pleural effusion
title Malignant melanoma presenting as an isolated pleural effusion
title_full Malignant melanoma presenting as an isolated pleural effusion
title_fullStr Malignant melanoma presenting as an isolated pleural effusion
title_full_unstemmed Malignant melanoma presenting as an isolated pleural effusion
title_short Malignant melanoma presenting as an isolated pleural effusion
title_sort malignant melanoma presenting as an isolated pleural effusion
topic Malignant melanoma
Pleura
Isolated pleural effusion
url https://www.monaldi-archives.org/index.php/macd/article/view/228
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AT jakhtar malignantmelanomapresentingasanisolatedpleuraleffusion
AT ubaneen malignantmelanomapresentingasanisolatedpleuraleffusion
AT nahmadkhan malignantmelanomapresentingasanisolatedpleuraleffusion
AT rbhargava malignantmelanomapresentingasanisolatedpleuraleffusion
AT zahmed malignantmelanomapresentingasanisolatedpleuraleffusion
AT mshahid malignantmelanomapresentingasanisolatedpleuraleffusion
AT mazfarsiddiqui malignantmelanomapresentingasanisolatedpleuraleffusion