Mir-190b negatively contributes to the Trypanosoma cruzi- infected cell survival by repressing PTEN protein expression

Mir-190b negatively contributes to the Trypanosoma cruzi- infected cell survival by repressing PTEN protein expression

Chagas disease, which is caused by the intracellular protozoanTrypanosoma cruzi, is a serious health problem in Latin America. The heart is one of the major organs affected by this parasitic infection. The pathogenesis of tissue remodelling, particularly regarding cardiomyocyte behaviour after paras...

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Bibliographic Details
Main Authors: Cíntia Júnia Monteiro, Suianne Letícia Antunes Mota, Lívia de Figueiredo Diniz, Maria Terezinha Bahia, Karen CM Moraes
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2015-12-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
cardiac cellular model
microRNA
PTEN
Trypanosoma cruzi
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762015000800996&lng=en&tlng=en

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