Differences in opioid prescription rates between patients with musculoskeletal disorders enrolled in coordinated ambulatory healthcare and patients receiving usual care: a retrospective observational cohort study

Objectives To compare opioid prescription rates between patients enrolled in coordinated ambulatory care and patients receiving usual care.Design In this retrospective cohort study, we analysed claims data for insured patients with non-specific/specific back pain or osteoarthritis of hip or knee fro...

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Main Authors: Marjan Van Den Akker, Ferdinand M Gerlach, Martin Beyer, Renate Klaassen-Mielke, Robin Brünn, Angelina Müller, Olga Anastasia Amberger, Anastasiya Glushan, Claudia Witte, Kateryna Karimova
Format: Article
Language:English
Published: BMJ Publishing Group 2022-08-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/12/8/e062657.full
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author Marjan Van Den Akker
Ferdinand M Gerlach
Martin Beyer
Renate Klaassen-Mielke
Robin Brünn
Angelina Müller
Olga Anastasia Amberger
Anastasiya Glushan
Claudia Witte
Kateryna Karimova
author_facet Marjan Van Den Akker
Ferdinand M Gerlach
Martin Beyer
Renate Klaassen-Mielke
Robin Brünn
Angelina Müller
Olga Anastasia Amberger
Anastasiya Glushan
Claudia Witte
Kateryna Karimova
author_sort Marjan Van Den Akker
collection DOAJ
description Objectives To compare opioid prescription rates between patients enrolled in coordinated ambulatory care and patients receiving usual care.Design In this retrospective cohort study, we analysed claims data for insured patients with non-specific/specific back pain or osteoarthritis of hip or knee from 2014 to 2017.Setting The study was based on administrative data provided by the statutory health insurance fund ‘Allgemeine Ortskrankenkasse’, in the state of Baden-Wurttemberg, Germany.Participants The intervention group consisted of patients enrolled in a coordinated ambulatory healthcare model; the control group included patients receiving usual care. Outcomes were overall strong and weak opioid prescriptions. Generalised linear regression models were used to analyse the effect of the intervention.Results Overall, 46 001 (non-specific 18 787/specific 27 214) patients with back pain and 19 366 patients with osteoarthritis belonged to the intervention group, and 7038 (2803/4235) and 963 patients to the control group, respectively. No significant difference in opioid prescriptions existed between the groups. However, the chance of being prescribed strong opioids was significantly lower in the intervention group (non-specific back pain: Odds Ratio (OR) 0.735, 95% Confidential Interval (CI) 0.563 to 0.960; specific back pain: OR 0.702, 95% CI 0.577 to 0.852; osteoarthritis: OR 0.644, 95% CI 0.464 to 0.892). The chance of being prescribed weak opioids was significantly higher in patients with specific back pain (OR 1.243, 95% CI 1.032 to 1.497) and osteoarthritis (OR 1.493, 95% CI 1.037 to 2.149) in the intervention group.Conclusion Coordinated ambulatory healthcare appears to be associated with a lower prescription rate for strong opioids in patients with chronic musculoskeletal disorders.Trial registration number German Clinical Trials Register (DRKS00017548).
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spelling doaj.art-4c5b51755fca4b1fa63199126066a0942022-12-22T02:51:51ZengBMJ Publishing GroupBMJ Open2044-60552022-08-0112810.1136/bmjopen-2022-062657Differences in opioid prescription rates between patients with musculoskeletal disorders enrolled in coordinated ambulatory healthcare and patients receiving usual care: a retrospective observational cohort studyMarjan Van Den Akker0Ferdinand M Gerlach1Martin Beyer2Renate Klaassen-Mielke3Robin Brünn4Angelina Müller5Olga Anastasia Amberger6Anastasiya Glushan7Claudia Witte8Kateryna Karimova9Institute of General Practice, Goethe-Universitat Frankfurt am Main, Frankfurt am Main, GermanyInstitute of General Practice, Goethe University Frankfurt, Frankfurt am Main, GermanyInstitute of General Practice, Goethe University Frankfurt, Frankfurt am Main, GermanyDepartment of Medical Informatics, Biometry and Epidemiology, Ruhr University, Bochum, GermanyInstitute of General Practice, Goethe-Universitat Frankfurt am Main, Frankfurt am Main, GermanyInstitute of General Practice, Goethe University, Frankfurt am Main, GermanyInstitute of General Practice, Goethe University, Frankfurt am Main, GermanyInstitute of General Practice, Goethe University, Frankfurt am Main, GermanyInstitute for Applied Quality Improvement and Research in Health Care, AQUA, Gottingen, GermanyInstitute of General Practice, Goethe University, Frankfurt am Main, GermanyObjectives To compare opioid prescription rates between patients enrolled in coordinated ambulatory care and patients receiving usual care.Design In this retrospective cohort study, we analysed claims data for insured patients with non-specific/specific back pain or osteoarthritis of hip or knee from 2014 to 2017.Setting The study was based on administrative data provided by the statutory health insurance fund ‘Allgemeine Ortskrankenkasse’, in the state of Baden-Wurttemberg, Germany.Participants The intervention group consisted of patients enrolled in a coordinated ambulatory healthcare model; the control group included patients receiving usual care. Outcomes were overall strong and weak opioid prescriptions. Generalised linear regression models were used to analyse the effect of the intervention.Results Overall, 46 001 (non-specific 18 787/specific 27 214) patients with back pain and 19 366 patients with osteoarthritis belonged to the intervention group, and 7038 (2803/4235) and 963 patients to the control group, respectively. No significant difference in opioid prescriptions existed between the groups. However, the chance of being prescribed strong opioids was significantly lower in the intervention group (non-specific back pain: Odds Ratio (OR) 0.735, 95% Confidential Interval (CI) 0.563 to 0.960; specific back pain: OR 0.702, 95% CI 0.577 to 0.852; osteoarthritis: OR 0.644, 95% CI 0.464 to 0.892). The chance of being prescribed weak opioids was significantly higher in patients with specific back pain (OR 1.243, 95% CI 1.032 to 1.497) and osteoarthritis (OR 1.493, 95% CI 1.037 to 2.149) in the intervention group.Conclusion Coordinated ambulatory healthcare appears to be associated with a lower prescription rate for strong opioids in patients with chronic musculoskeletal disorders.Trial registration number German Clinical Trials Register (DRKS00017548).https://bmjopen.bmj.com/content/12/8/e062657.full
spellingShingle Marjan Van Den Akker
Ferdinand M Gerlach
Martin Beyer
Renate Klaassen-Mielke
Robin Brünn
Angelina Müller
Olga Anastasia Amberger
Anastasiya Glushan
Claudia Witte
Kateryna Karimova
Differences in opioid prescription rates between patients with musculoskeletal disorders enrolled in coordinated ambulatory healthcare and patients receiving usual care: a retrospective observational cohort study
BMJ Open
title Differences in opioid prescription rates between patients with musculoskeletal disorders enrolled in coordinated ambulatory healthcare and patients receiving usual care: a retrospective observational cohort study
title_full Differences in opioid prescription rates between patients with musculoskeletal disorders enrolled in coordinated ambulatory healthcare and patients receiving usual care: a retrospective observational cohort study
title_fullStr Differences in opioid prescription rates between patients with musculoskeletal disorders enrolled in coordinated ambulatory healthcare and patients receiving usual care: a retrospective observational cohort study
title_full_unstemmed Differences in opioid prescription rates between patients with musculoskeletal disorders enrolled in coordinated ambulatory healthcare and patients receiving usual care: a retrospective observational cohort study
title_short Differences in opioid prescription rates between patients with musculoskeletal disorders enrolled in coordinated ambulatory healthcare and patients receiving usual care: a retrospective observational cohort study
title_sort differences in opioid prescription rates between patients with musculoskeletal disorders enrolled in coordinated ambulatory healthcare and patients receiving usual care a retrospective observational cohort study
url https://bmjopen.bmj.com/content/12/8/e062657.full
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