Evaluating the impact of three progestin-based hormonal contraceptive methods on immunologic changes in the female genital tract and systemically (CHIME Study): a prospective cohort study protocol

Evaluating the impact of three progestin-based hormonal contraceptive methods on immunologic changes in the female genital tract and systemically (CHIME Study): a prospective cohort study protocol

Abstract Background Gonadal hormones can modify immune function, which may impact susceptibility to infectious diseases, including Human Immunodeficiency Virus (HIV). There is limited knowledge about how hormonal contraceptives (HC) influence the immune response during the course of use. The CHIME s...

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Bibliographic Details
Main Authors: Lisa B. Haddad, Gina Bailey Herring, C. Christina Mehta, Tyree Staple, Marisa R. Young, Sakthivel Govindaraj, Vijayakumar Velu, Alicia K. Smith
Format: Article
Language:English
Published: BMC 2022-11-01
Series:BMC Women's Health
Subjects:
Progestin contraception
Immunology
Female genital tract
Vaginal microenvironment
HIV target cells
Online Access:https://doi.org/10.1186/s12905-022-02053-w

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