Inhibition of HIV-1 integrase nuclear import and replication by a peptide bearing integrase putative nuclear localization signal

Inhibition of HIV-1 integrase nuclear import and replication by a peptide bearing integrase putative nuclear localization signal

<p>Abstract</p> <p>Background</p> <p>The integrase (IN) of human immunodeficiency virus type 1 (HIV-1) has been implicated in different steps during viral replication, including nuclear import of the viral pre-integration complex. The exact mechanisms underlying the nuc...

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Bibliographic Details
Main Authors: Waigmann Elisabeth, Graessmann Adolf, Melamed-Book Naomi, Rosenbluh Joseph, Armon-Omer Ayelet, Levin Aviad, Loyter Abraham
Format: Article
Language:English
Published: BMC 2009-12-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/6/1/112

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