Deciphering the Interactome of Neisseria meningitidis With Human Brain Microvascular Endothelial Cells

Deciphering the Interactome of Neisseria meningitidis With Human Brain Microvascular Endothelial Cells

Neisseria meningitidis is able to translocate the blood-brain barrier and cause meningitis. Bacterial translocation is a crucial step in the onset of neuroinvasion that involves interactions between pathogen surface proteins and host cells receptors. In this study, we applied a systematic workflow t...

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Bibliographic Details
Main Authors: Evelína Kánová, Irene Jiménez-Munguía, Petra Majerová, Zuzana Tkáčová, Katarína Bhide, Patrícia Mertinková, Lucia Pulzová, Andrej Kováč, Mangesh Bhide
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Microbiology
Subjects:
Neisseria meningitidis
hBMECs
bioinformatic pipeline
BBB
ligands
interactome
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.02294/full

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