The Association between Serum Lactate Level and Post CABG Complications in Cardiac Patients
Background: The aim of this study was to evaluate the relationship between postoperative serum lactate levels and outcome in patients undergoing coronary artery bypass graft surgery (CABG) and verify the clinical impact of hyperlactatemia (HL) during CABG in terms of postoperative morbidity and mort...
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| Format: | Article |
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Isfahan University of Medical Sciences
2011-04-01
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| Series: | مجله دانشکده پزشکی اصفهان |
| Subjects: | |
| Online Access: | http://jims.mui.ac.ir/index.php/jims/article/view/728 |
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| author | Mohsen Mirmohammad-Sadeghi Ali Etesampour Mojgan Gharipour Mohammad Saeidi Pouya Mirmohammad-sadeghi Amjad Kiani Hamid Shamsolkotabi Niloufar Farahmand Afshan Akhavan Tabib |
| author_facet | Mohsen Mirmohammad-Sadeghi Ali Etesampour Mojgan Gharipour Mohammad Saeidi Pouya Mirmohammad-sadeghi Amjad Kiani Hamid Shamsolkotabi Niloufar Farahmand Afshan Akhavan Tabib |
| author_sort | Mohsen Mirmohammad-Sadeghi |
| collection | DOAJ |
| description | Background: The aim of this study was to evaluate the relationship between postoperative serum lactate levels and outcome in patients undergoing coronary artery bypass graft surgery (CABG) and verify the clinical impact of hyperlactatemia (HL) during CABG in terms of postoperative morbidity and mortality rate.
Methods: In this prospective study, 92 patients underwent open heart surgery. Demographic data, lactate levels, PH, 48 hours serum creatinin after surgery (mg per cent), left ventricular ejection fraction, Inotropic Drugs and the duration of use and the duration of intensive care unit (ICU) admission t and deaths were collected.
Finding: Mortality rate was 3.3 percent, the average duration of hospitalization was 8.8 days and the duration of ICU admission was 47.27 hours. In 82.6% of the patients increased lactic acid was observed; while 17.4% of patients had a low lactate serum concentration during ICU admission.
Conclusion: The findings of this study showed an association between lactate serum levels and the duration of ICU admission and duration of hospitalization, so hyperlactatemia could be a prognostic factor and could predict the mortality and the severity of complications in the patients undergone CABG. |
| first_indexed | 2024-03-12T19:03:10Z |
| format | Article |
| id | doaj.art-4c60bfa4bb694ee080f2288025f81def |
| institution | Directory Open Access Journal |
| issn | 1027-7595 1735-854X |
| language | fas |
| last_indexed | 2024-03-12T19:03:10Z |
| publishDate | 2011-04-01 |
| publisher | Isfahan University of Medical Sciences |
| record_format | Article |
| series | مجله دانشکده پزشکی اصفهان |
| spelling | doaj.art-4c60bfa4bb694ee080f2288025f81def2023-08-02T06:28:16ZfasIsfahan University of Medical Sciencesمجله دانشکده پزشکی اصفهان1027-75951735-854X2011-04-0129128147154622The Association between Serum Lactate Level and Post CABG Complications in Cardiac PatientsMohsen Mirmohammad-Sadeghi0Ali Etesampour1Mojgan Gharipour2Mohammad Saeidi3Pouya Mirmohammad-sadeghi4Amjad Kiani5Hamid Shamsolkotabi6Niloufar Farahmand7Afshan Akhavan Tabib8Assistant Professor, Department of Cardiosurgery, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.Cardiologist, Delasa Research Center, Isfahan, Iran.Researcher, Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.Assistant Professor, Department of Cardiosurgery, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.Medical Student, Student Research Committee, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.Anesthesiologist, Isfahan University of Medical Sciences, Isfahan, Iran.Cardiologist, Delasa Research Center, Isfahan, Iran.Nurse, Delasa Research Center, Isfahan, Iran.General Practitioner, Isfahan Cardiovascular Research Center, Isfahan cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.Background: The aim of this study was to evaluate the relationship between postoperative serum lactate levels and outcome in patients undergoing coronary artery bypass graft surgery (CABG) and verify the clinical impact of hyperlactatemia (HL) during CABG in terms of postoperative morbidity and mortality rate. Methods: In this prospective study, 92 patients underwent open heart surgery. Demographic data, lactate levels, PH, 48 hours serum creatinin after surgery (mg per cent), left ventricular ejection fraction, Inotropic Drugs and the duration of use and the duration of intensive care unit (ICU) admission t and deaths were collected. Finding: Mortality rate was 3.3 percent, the average duration of hospitalization was 8.8 days and the duration of ICU admission was 47.27 hours. In 82.6% of the patients increased lactic acid was observed; while 17.4% of patients had a low lactate serum concentration during ICU admission. Conclusion: The findings of this study showed an association between lactate serum levels and the duration of ICU admission and duration of hospitalization, so hyperlactatemia could be a prognostic factor and could predict the mortality and the severity of complications in the patients undergone CABG.http://jims.mui.ac.ir/index.php/jims/article/view/728Cardiac surgerySerum lactateOutcome |
| spellingShingle | Mohsen Mirmohammad-Sadeghi Ali Etesampour Mojgan Gharipour Mohammad Saeidi Pouya Mirmohammad-sadeghi Amjad Kiani Hamid Shamsolkotabi Niloufar Farahmand Afshan Akhavan Tabib The Association between Serum Lactate Level and Post CABG Complications in Cardiac Patients مجله دانشکده پزشکی اصفهان Cardiac surgery Serum lactate Outcome |
| title | The Association between Serum Lactate Level and Post CABG Complications in Cardiac Patients |
| title_full | The Association between Serum Lactate Level and Post CABG Complications in Cardiac Patients |
| title_fullStr | The Association between Serum Lactate Level and Post CABG Complications in Cardiac Patients |
| title_full_unstemmed | The Association between Serum Lactate Level and Post CABG Complications in Cardiac Patients |
| title_short | The Association between Serum Lactate Level and Post CABG Complications in Cardiac Patients |
| title_sort | association between serum lactate level and post cabg complications in cardiac patients |
| topic | Cardiac surgery Serum lactate Outcome |
| url | http://jims.mui.ac.ir/index.php/jims/article/view/728 |
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