Methods for Radiolabelling Nanoparticles: PET Use (Part 2)
The use of radiolabelled nanoparticles (NPs) is a promising nuclear medicine tool for diagnostic and therapeutic purposes. Thanks to the heterogeneity of their material (organic or inorganic) and their unique physical and chemical characteristics, they are highly versatile for their use in several m...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-10-01
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| Series: | Biomolecules |
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| Online Access: | https://www.mdpi.com/2218-273X/12/10/1517 |
| _version_ | 1827651304218951680 |
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| author | Valeria Bentivoglio Michela Varani Chiara Lauri Danilo Ranieri Alberto Signore |
| author_facet | Valeria Bentivoglio Michela Varani Chiara Lauri Danilo Ranieri Alberto Signore |
| author_sort | Valeria Bentivoglio |
| collection | DOAJ |
| description | The use of radiolabelled nanoparticles (NPs) is a promising nuclear medicine tool for diagnostic and therapeutic purposes. Thanks to the heterogeneity of their material (organic or inorganic) and their unique physical and chemical characteristics, they are highly versatile for their use in several medical applications. In particular, they have shown interesting results as radiolabelled probes for positron emission tomography (PET) imaging. The high variability of NP types and the possibility to use several isotopes in the radiolabelling process implies different radiolabelling methods that have been applied over the previous years. In this review, we compare and summarize the different methods for NP radiolabelling with the most frequently used PET isotopes. |
| first_indexed | 2024-03-09T20:35:51Z |
| format | Article |
| id | doaj.art-4c6337f15e5940d8bf925c8e4d932d58 |
| institution | Directory Open Access Journal |
| issn | 2218-273X |
| language | English |
| last_indexed | 2024-03-09T20:35:51Z |
| publishDate | 2022-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomolecules |
| spelling | doaj.art-4c6337f15e5940d8bf925c8e4d932d582023-11-23T23:09:56ZengMDPI AGBiomolecules2218-273X2022-10-011210151710.3390/biom12101517Methods for Radiolabelling Nanoparticles: PET Use (Part 2)Valeria Bentivoglio0Michela Varani1Chiara Lauri2Danilo Ranieri3Alberto Signore4Nuclear Medicine Unit, Department of Medical-Surgical Sciences and of Translational Medicine, Faculty of Medicine and Psychology, “Sapienza” University of Rome, 00185 Rome, ItalyNuclear Medicine Unit, Department of Medical-Surgical Sciences and of Translational Medicine, Faculty of Medicine and Psychology, “Sapienza” University of Rome, 00185 Rome, ItalyNuclear Medicine Unit, Department of Medical-Surgical Sciences and of Translational Medicine, Faculty of Medicine and Psychology, “Sapienza” University of Rome, 00185 Rome, ItalyDepartment of Clinical and Molecular Medicine, Faculty of Medicine and Psychology, “Sapienza” University of Rome, 00185 Rome, ItalyNuclear Medicine Unit, Department of Medical-Surgical Sciences and of Translational Medicine, Faculty of Medicine and Psychology, “Sapienza” University of Rome, 00185 Rome, ItalyThe use of radiolabelled nanoparticles (NPs) is a promising nuclear medicine tool for diagnostic and therapeutic purposes. Thanks to the heterogeneity of their material (organic or inorganic) and their unique physical and chemical characteristics, they are highly versatile for their use in several medical applications. In particular, they have shown interesting results as radiolabelled probes for positron emission tomography (PET) imaging. The high variability of NP types and the possibility to use several isotopes in the radiolabelling process implies different radiolabelling methods that have been applied over the previous years. In this review, we compare and summarize the different methods for NP radiolabelling with the most frequently used PET isotopes.https://www.mdpi.com/2218-273X/12/10/1517nanoparticlesnanotechnologynuclear medicineradiolabellingPET/CT |
| spellingShingle | Valeria Bentivoglio Michela Varani Chiara Lauri Danilo Ranieri Alberto Signore Methods for Radiolabelling Nanoparticles: PET Use (Part 2) Biomolecules nanoparticles nanotechnology nuclear medicine radiolabelling PET/CT |
| title | Methods for Radiolabelling Nanoparticles: PET Use (Part 2) |
| title_full | Methods for Radiolabelling Nanoparticles: PET Use (Part 2) |
| title_fullStr | Methods for Radiolabelling Nanoparticles: PET Use (Part 2) |
| title_full_unstemmed | Methods for Radiolabelling Nanoparticles: PET Use (Part 2) |
| title_short | Methods for Radiolabelling Nanoparticles: PET Use (Part 2) |
| title_sort | methods for radiolabelling nanoparticles pet use part 2 |
| topic | nanoparticles nanotechnology nuclear medicine radiolabelling PET/CT |
| url | https://www.mdpi.com/2218-273X/12/10/1517 |
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