Effect of natural polymer materials on skin healing based on internal wound microenvironment: a review

The concept of wound microenvironment has been discussed for a long time. However, the mechanism of the internal microenvironment is relatively little studied. Here, we present a systematic discussion on the mechanism of natural polymer materials such as chitosan, cellulose, collagen and hyaluronic...

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Main Authors: Ying Yang, Bingbing Li, Mengxin Wang, Shicong Pan, Yu Wang, Jinhui Gu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Chemistry
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2023.1257915/full
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author Ying Yang
Bingbing Li
Mengxin Wang
Shicong Pan
Yu Wang
Jinhui Gu
author_facet Ying Yang
Bingbing Li
Mengxin Wang
Shicong Pan
Yu Wang
Jinhui Gu
author_sort Ying Yang
collection DOAJ
description The concept of wound microenvironment has been discussed for a long time. However, the mechanism of the internal microenvironment is relatively little studied. Here, we present a systematic discussion on the mechanism of natural polymer materials such as chitosan, cellulose, collagen and hyaluronic acid through their effects on the internal wound microenvironment and regulation of wound healing, in order to more comprehensively explain the concept of wound microenvironment and provide a reference for further innovative clinical for the preparation and application of wound healing agents.
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spelling doaj.art-4c6d4f9a346d44769a0021d83fedd4ad2023-09-05T06:49:19ZengFrontiers Media S.A.Frontiers in Chemistry2296-26462023-09-011110.3389/fchem.2023.12579151257915Effect of natural polymer materials on skin healing based on internal wound microenvironment: a reviewYing Yang0Bingbing Li1Mengxin Wang2Shicong Pan3Yu Wang4Jinhui Gu5The People’s Hospital of SND, Suzhou, Jiangsu, ChinaNanjing University of Chinese Medicine, Nanjing, Jiangsu, ChinaNanjing University of Chinese Medicine, Nanjing, Jiangsu, ChinaGuzhou University of Traditional Chinese Medicine, Guiyang, Guizhou, ChinaThe People’s Hospital of SND, Suzhou, Jiangsu, ChinaSuzhou Hospital of Traditional Chinese Medicine Affiliated to Nanjing University of Chinese Medicine, Suzhou, Jiangsu, ChinaThe concept of wound microenvironment has been discussed for a long time. However, the mechanism of the internal microenvironment is relatively little studied. Here, we present a systematic discussion on the mechanism of natural polymer materials such as chitosan, cellulose, collagen and hyaluronic acid through their effects on the internal wound microenvironment and regulation of wound healing, in order to more comprehensively explain the concept of wound microenvironment and provide a reference for further innovative clinical for the preparation and application of wound healing agents.https://www.frontiersin.org/articles/10.3389/fchem.2023.1257915/fullnatural polymer materialswound internal environmentcollagenhyaluronic acidchitosan
spellingShingle Ying Yang
Bingbing Li
Mengxin Wang
Shicong Pan
Yu Wang
Jinhui Gu
Effect of natural polymer materials on skin healing based on internal wound microenvironment: a review
Frontiers in Chemistry
natural polymer materials
wound internal environment
collagen
hyaluronic acid
chitosan
title Effect of natural polymer materials on skin healing based on internal wound microenvironment: a review
title_full Effect of natural polymer materials on skin healing based on internal wound microenvironment: a review
title_fullStr Effect of natural polymer materials on skin healing based on internal wound microenvironment: a review
title_full_unstemmed Effect of natural polymer materials on skin healing based on internal wound microenvironment: a review
title_short Effect of natural polymer materials on skin healing based on internal wound microenvironment: a review
title_sort effect of natural polymer materials on skin healing based on internal wound microenvironment a review
topic natural polymer materials
wound internal environment
collagen
hyaluronic acid
chitosan
url https://www.frontiersin.org/articles/10.3389/fchem.2023.1257915/full
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AT mengxinwang effectofnaturalpolymermaterialsonskinhealingbasedoninternalwoundmicroenvironmentareview
AT shicongpan effectofnaturalpolymermaterialsonskinhealingbasedoninternalwoundmicroenvironmentareview
AT yuwang effectofnaturalpolymermaterialsonskinhealingbasedoninternalwoundmicroenvironmentareview
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