Regulatory T cells expanded from HIV-1-infected individuals maintain phenotype, TCR repertoire and suppressive capacity.
While modulation of regulatory T cell (Treg) function and adoptive Treg transfer are being explored as therapeutic modalities in the context of autoimmune diseases, transplantation and cancer, their role in HIV-1 pathogenesis remains less well defined. Controversy persists regarding their beneficial...
Main Authors: | Mathieu Angin, Paul L Klarenbeek, Melanie King, Siddhartha M Sharma, Eshia S Moodley, Ashley Rezai, Alicja Piechocka-Trocha, Ildiko Toth, Andrew T Chan, Philip J Goulder, Thumbi Ndung'u, Douglas S Kwon, Marylyn M Addo |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3911933?pdf=render |
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