Activity of kallikrein-kinin system in children in norm and at some pathological states

Proteolytic systems of tissue and blood plasma take part in the processes of adaptation and protection of an organism, as well as in development of pathological reactions. We have studied the activity of kallikrein, kallikreinogen, angiotensine transforming enzyme, α1-protease inhibitor, and α2-macr...

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Main Authors: Ye. I. Kondratiyeva, T. Ye. Tropova, G. A. Sukhanova, A. A. Terentiyeva, T. S. Krivonogova, V. V. Gorev, N. P. Stepanenko, Ye. Yu. Tyuteva
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2009-08-01
Series:Бюллетень сибирской медицины
Subjects:
Online Access:https://bulletin.ssmu.ru/jour/article/view/1919
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author Ye. I. Kondratiyeva
T. Ye. Tropova
G. A. Sukhanova
A. A. Terentiyeva
T. S. Krivonogova
V. V. Gorev
N. P. Stepanenko
Ye. Yu. Tyuteva
author_facet Ye. I. Kondratiyeva
T. Ye. Tropova
G. A. Sukhanova
A. A. Terentiyeva
T. S. Krivonogova
V. V. Gorev
N. P. Stepanenko
Ye. Yu. Tyuteva
author_sort Ye. I. Kondratiyeva
collection DOAJ
description Proteolytic systems of tissue and blood plasma take part in the processes of adaptation and protection of an organism, as well as in development of pathological reactions. We have studied the activity of kallikrein, kallikreinogen, angiotensine transforming enzyme, α1-protease inhibitor, and α2-macroglobulin in healthy children in different age periods, in newborns with hypoxic-ischemic encephalopathy, in children with infectious-inflammatory diseases of the urinary system, obesity, and metabolic syndrome.The activity of the kallikrein-kinin system was increased in all the groups against the background of the decreased inhibitory activity of blood plasma of different intensity, which can be used for the prediction of the course of diseases.
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spelling doaj.art-4c7056d9fc12471b922ab02818a85b072023-03-13T09:58:12ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842009-08-0184(2)616910.20538/1682-0363-2009-4(2)-61-691412Activity of kallikrein-kinin system in children in norm and at some pathological statesYe. I. Kondratiyeva0T. Ye. Tropova1G. A. Sukhanova2A. A. Terentiyeva3T. S. Krivonogova4V. V. Gorev5N. P. Stepanenko6Ye. Yu. Tyuteva7Сибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетТомский НИИ курортологии и физиотерапии ФМБА РоссииСибирский государственный медицинский университетProteolytic systems of tissue and blood plasma take part in the processes of adaptation and protection of an organism, as well as in development of pathological reactions. We have studied the activity of kallikrein, kallikreinogen, angiotensine transforming enzyme, α1-protease inhibitor, and α2-macroglobulin in healthy children in different age periods, in newborns with hypoxic-ischemic encephalopathy, in children with infectious-inflammatory diseases of the urinary system, obesity, and metabolic syndrome.The activity of the kallikrein-kinin system was increased in all the groups against the background of the decreased inhibitory activity of blood plasma of different intensity, which can be used for the prediction of the course of diseases.https://bulletin.ssmu.ru/jour/article/view/1919калликреинкалликреиногенангиотензинпревращающий ферментα1-протеазный ингибиторα2- макроглобулиндети
spellingShingle Ye. I. Kondratiyeva
T. Ye. Tropova
G. A. Sukhanova
A. A. Terentiyeva
T. S. Krivonogova
V. V. Gorev
N. P. Stepanenko
Ye. Yu. Tyuteva
Activity of kallikrein-kinin system in children in norm and at some pathological states
Бюллетень сибирской медицины
калликреин
калликреиноген
ангиотензинпревращающий фермент
α1-протеазный ингибитор
α2- макроглобулин
дети
title Activity of kallikrein-kinin system in children in norm and at some pathological states
title_full Activity of kallikrein-kinin system in children in norm and at some pathological states
title_fullStr Activity of kallikrein-kinin system in children in norm and at some pathological states
title_full_unstemmed Activity of kallikrein-kinin system in children in norm and at some pathological states
title_short Activity of kallikrein-kinin system in children in norm and at some pathological states
title_sort activity of kallikrein kinin system in children in norm and at some pathological states
topic калликреин
калликреиноген
ангиотензинпревращающий фермент
α1-протеазный ингибитор
α2- макроглобулин
дети
url https://bulletin.ssmu.ru/jour/article/view/1919
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AT gasukhanova activityofkallikreinkininsysteminchildreninnormandatsomepathologicalstates
AT aaterentiyeva activityofkallikreinkininsysteminchildreninnormandatsomepathologicalstates
AT tskrivonogova activityofkallikreinkininsysteminchildreninnormandatsomepathologicalstates
AT vvgorev activityofkallikreinkininsysteminchildreninnormandatsomepathologicalstates
AT npstepanenko activityofkallikreinkininsysteminchildreninnormandatsomepathologicalstates
AT yeyutyuteva activityofkallikreinkininsysteminchildreninnormandatsomepathologicalstates