RNA Helicase A Regulates the Replication of RNA Viruses
The RNA helicase A (RHA) is a member of DExH-box helicases and characterized by two double-stranded RNA binding domains at the N-terminus. RHA unwinds double-stranded RNA in vitro and is involved in RNA metabolisms in the cell. RHA is also hijacked by a variety of RNA viruses to facilitate virus rep...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-02-01
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| Series: | Viruses |
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| Online Access: | https://www.mdpi.com/1999-4915/13/3/361 |
| _version_ | 1797395224925831168 |
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| author | Rui-Zhu Shi Yuan-Qing Pan Li Xing |
| author_facet | Rui-Zhu Shi Yuan-Qing Pan Li Xing |
| author_sort | Rui-Zhu Shi |
| collection | DOAJ |
| description | The RNA helicase A (RHA) is a member of DExH-box helicases and characterized by two double-stranded RNA binding domains at the N-terminus. RHA unwinds double-stranded RNA in vitro and is involved in RNA metabolisms in the cell. RHA is also hijacked by a variety of RNA viruses to facilitate virus replication. Herein, this review will provide an overview of the role of RHA in the replication of RNA viruses. |
| first_indexed | 2024-03-09T00:32:21Z |
| format | Article |
| id | doaj.art-4c7558510aaf4d718c1ae66659b152ec |
| institution | Directory Open Access Journal |
| issn | 1999-4915 |
| language | English |
| last_indexed | 2024-03-09T00:32:21Z |
| publishDate | 2021-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj.art-4c7558510aaf4d718c1ae66659b152ec2023-12-11T18:25:37ZengMDPI AGViruses1999-49152021-02-0113336110.3390/v13030361RNA Helicase A Regulates the Replication of RNA VirusesRui-Zhu Shi0Yuan-Qing Pan1Li Xing2Institute of Biomedical Sciences, Shanxi University, 92 Wucheng Road, Taiyuan 030006, ChinaInstitute of Biomedical Sciences, Shanxi University, 92 Wucheng Road, Taiyuan 030006, ChinaInstitute of Biomedical Sciences, Shanxi University, 92 Wucheng Road, Taiyuan 030006, ChinaThe RNA helicase A (RHA) is a member of DExH-box helicases and characterized by two double-stranded RNA binding domains at the N-terminus. RHA unwinds double-stranded RNA in vitro and is involved in RNA metabolisms in the cell. RHA is also hijacked by a variety of RNA viruses to facilitate virus replication. Herein, this review will provide an overview of the role of RHA in the replication of RNA viruses.https://www.mdpi.com/1999-4915/13/3/361RNA helicase ARNA virustranscriptiontranslationreplication |
| spellingShingle | Rui-Zhu Shi Yuan-Qing Pan Li Xing RNA Helicase A Regulates the Replication of RNA Viruses Viruses RNA helicase A RNA virus transcription translation replication |
| title | RNA Helicase A Regulates the Replication of RNA Viruses |
| title_full | RNA Helicase A Regulates the Replication of RNA Viruses |
| title_fullStr | RNA Helicase A Regulates the Replication of RNA Viruses |
| title_full_unstemmed | RNA Helicase A Regulates the Replication of RNA Viruses |
| title_short | RNA Helicase A Regulates the Replication of RNA Viruses |
| title_sort | rna helicase a regulates the replication of rna viruses |
| topic | RNA helicase A RNA virus transcription translation replication |
| url | https://www.mdpi.com/1999-4915/13/3/361 |
| work_keys_str_mv | AT ruizhushi rnahelicasearegulatesthereplicationofrnaviruses AT yuanqingpan rnahelicasearegulatesthereplicationofrnaviruses AT lixing rnahelicasearegulatesthereplicationofrnaviruses |