Application of Deep Convolutional Neural Networks in the Diagnosis of Osteoporosis

The aim of this study was to assess the possibility of using deep convolutional neural networks (DCNNs) to develop an effective method for diagnosing osteoporosis based on CT images of the spine. The research material included the CT images of L1 spongy tissue belonging to 100 patients (50 healthy a...

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Main Authors: Róża Dzierżak, Zbigniew Omiotek
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Sensors
Subjects:
Online Access:https://www.mdpi.com/1424-8220/22/21/8189
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author Róża Dzierżak
Zbigniew Omiotek
author_facet Róża Dzierżak
Zbigniew Omiotek
author_sort Róża Dzierżak
collection DOAJ
description The aim of this study was to assess the possibility of using deep convolutional neural networks (DCNNs) to develop an effective method for diagnosing osteoporosis based on CT images of the spine. The research material included the CT images of L1 spongy tissue belonging to 100 patients (50 healthy and 50 diagnosed with osteoporosis). Six pre-trained DCNN architectures with different topological depths (VGG16, VGG19, MobileNetV2, Xception, ResNet50, and InceptionResNetV2) were used in the study. The best results were obtained for the VGG16 model characterised by the lowest topological depth (ACC = 95%, TPR = 96%, and TNR = 94%). A specific challenge during the study was the relatively small (for deep learning) number of observations (400 images). This problem was solved using DCNN models pre-trained on a large dataset and a data augmentation technique. The obtained results allow us to conclude that the transfer learning technique yields satisfactory results during the construction of deep models for the diagnosis of osteoporosis based on small datasets of CT images of the spine.
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spelling doaj.art-4c77cc9bd1db46c8a46856eae1f661d02023-11-24T06:44:05ZengMDPI AGSensors1424-82202022-10-012221818910.3390/s22218189Application of Deep Convolutional Neural Networks in the Diagnosis of OsteoporosisRóża Dzierżak0Zbigniew Omiotek1Department of Electronics and Information Technology, Lublin University of Technology, ul. Nadbystrzycka 38A, 20-618 Lublin, PolandDepartment of Electronics and Information Technology, Lublin University of Technology, ul. Nadbystrzycka 38A, 20-618 Lublin, PolandThe aim of this study was to assess the possibility of using deep convolutional neural networks (DCNNs) to develop an effective method for diagnosing osteoporosis based on CT images of the spine. The research material included the CT images of L1 spongy tissue belonging to 100 patients (50 healthy and 50 diagnosed with osteoporosis). Six pre-trained DCNN architectures with different topological depths (VGG16, VGG19, MobileNetV2, Xception, ResNet50, and InceptionResNetV2) were used in the study. The best results were obtained for the VGG16 model characterised by the lowest topological depth (ACC = 95%, TPR = 96%, and TNR = 94%). A specific challenge during the study was the relatively small (for deep learning) number of observations (400 images). This problem was solved using DCNN models pre-trained on a large dataset and a data augmentation technique. The obtained results allow us to conclude that the transfer learning technique yields satisfactory results during the construction of deep models for the diagnosis of osteoporosis based on small datasets of CT images of the spine.https://www.mdpi.com/1424-8220/22/21/8189osteoporosisconvolutional neural networksdeep learningVGG16image classificationneural networks
spellingShingle Róża Dzierżak
Zbigniew Omiotek
Application of Deep Convolutional Neural Networks in the Diagnosis of Osteoporosis
Sensors
osteoporosis
convolutional neural networks
deep learning
VGG16
image classification
neural networks
title Application of Deep Convolutional Neural Networks in the Diagnosis of Osteoporosis
title_full Application of Deep Convolutional Neural Networks in the Diagnosis of Osteoporosis
title_fullStr Application of Deep Convolutional Neural Networks in the Diagnosis of Osteoporosis
title_full_unstemmed Application of Deep Convolutional Neural Networks in the Diagnosis of Osteoporosis
title_short Application of Deep Convolutional Neural Networks in the Diagnosis of Osteoporosis
title_sort application of deep convolutional neural networks in the diagnosis of osteoporosis
topic osteoporosis
convolutional neural networks
deep learning
VGG16
image classification
neural networks
url https://www.mdpi.com/1424-8220/22/21/8189
work_keys_str_mv AT rozadzierzak applicationofdeepconvolutionalneuralnetworksinthediagnosisofosteoporosis
AT zbigniewomiotek applicationofdeepconvolutionalneuralnetworksinthediagnosisofosteoporosis