Hypolipidemic activity of Piper betel in high fat diet induced hyperlipidemic rat
Objective: To evaluate the hypolipidemic effect of Piper betel (P. betel) in high fat diet induced hyperlipidemia rat. Methods: The methanol leaf extract was tested for hypolipidemic effect in the albino rats at the selected optimum dosage of 250 mg/kg body weight and administered orally. Adult male...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2014-01-01
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| Series: | Journal of Acute Disease |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2221618914600299 |
| _version_ | 1818837147535278080 |
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| author | Thirunavukkarasu Thirumalai Narayanaswamy Tamilselvan Ernest David |
| author_facet | Thirunavukkarasu Thirumalai Narayanaswamy Tamilselvan Ernest David |
| author_sort | Thirunavukkarasu Thirumalai |
| collection | DOAJ |
| description | Objective: To evaluate the hypolipidemic effect of Piper betel (P. betel) in high fat diet induced hyperlipidemia rat.
Methods: The methanol leaf extract was tested for hypolipidemic effect in the albino rats at the selected optimum dosage of 250 mg/kg body weight and administered orally. Adult male albino rats of six numbers in each group were undertaken study and evaluated.
Results: In group II animals, the activity levels of serum total cholesterol (TC), triglycerides (TG), low density lipoprotein (LDL) and very low density lipoprotein-cholesterol (VLDL) were significantly enhanced when compared to that of normal rat.
Conclusion: It could be said that the methanolic leaf extract of P. betel exhibited a significant hypolipidemic effect. |
| first_indexed | 2024-12-19T03:17:53Z |
| format | Article |
| id | doaj.art-4c7877f2049e4dafb3b9f569712d1886 |
| institution | Directory Open Access Journal |
| issn | 2221-6189 |
| language | English |
| last_indexed | 2024-12-19T03:17:53Z |
| publishDate | 2014-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Acute Disease |
| spelling | doaj.art-4c7877f2049e4dafb3b9f569712d18862022-12-21T20:37:51ZengWolters Kluwer Medknow PublicationsJournal of Acute Disease2221-61892014-01-013213113510.1016/S2221-6189(14)60029-9Hypolipidemic activity of Piper betel in high fat diet induced hyperlipidemic ratThirunavukkarasu Thirumalai0Narayanaswamy Tamilselvan1Ernest David2P.G. and Research Department of Zoology, Voorhees College, Physiology Wing, Vellore-632001(T.N.), IndiaP.G. and Research Department of Zoology, Voorhees College, Physiology Wing, Vellore-632001(T.N.), IndiaDepartment of Biotechnology, Thiruvalluvar University, Serkadu, Vellore-632115(T.N.), IndiaObjective: To evaluate the hypolipidemic effect of Piper betel (P. betel) in high fat diet induced hyperlipidemia rat. Methods: The methanol leaf extract was tested for hypolipidemic effect in the albino rats at the selected optimum dosage of 250 mg/kg body weight and administered orally. Adult male albino rats of six numbers in each group were undertaken study and evaluated. Results: In group II animals, the activity levels of serum total cholesterol (TC), triglycerides (TG), low density lipoprotein (LDL) and very low density lipoprotein-cholesterol (VLDL) were significantly enhanced when compared to that of normal rat. Conclusion: It could be said that the methanolic leaf extract of P. betel exhibited a significant hypolipidemic effect.http://www.sciencedirect.com/science/article/pii/S2221618914600299Cardiovascular diseaseHyperlipidemiaMedicinal plantPiper betelHigh fat diet |
| spellingShingle | Thirunavukkarasu Thirumalai Narayanaswamy Tamilselvan Ernest David Hypolipidemic activity of Piper betel in high fat diet induced hyperlipidemic rat Journal of Acute Disease Cardiovascular disease Hyperlipidemia Medicinal plant Piper betel High fat diet |
| title | Hypolipidemic activity of Piper betel in high fat diet induced hyperlipidemic rat |
| title_full | Hypolipidemic activity of Piper betel in high fat diet induced hyperlipidemic rat |
| title_fullStr | Hypolipidemic activity of Piper betel in high fat diet induced hyperlipidemic rat |
| title_full_unstemmed | Hypolipidemic activity of Piper betel in high fat diet induced hyperlipidemic rat |
| title_short | Hypolipidemic activity of Piper betel in high fat diet induced hyperlipidemic rat |
| title_sort | hypolipidemic activity of piper betel in high fat diet induced hyperlipidemic rat |
| topic | Cardiovascular disease Hyperlipidemia Medicinal plant Piper betel High fat diet |
| url | http://www.sciencedirect.com/science/article/pii/S2221618914600299 |
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