Magnolol potently suppressed lipopolysaccharide-induced iNOS and COX-2 expression via downregulating MAPK and NF-κB signaling pathways

Magnolol potently suppressed lipopolysaccharide-induced iNOS and COX-2 expression via downregulating MAPK and NF-κB signaling pathways

Magnolol is a hydroxylated biphenyl compound from the bark of Magnolia officinalis that has been reported to have various biological properties including anti-inflammation. However, the molecular mechanism of anti-inflammation remains unclear although it has been suggested that magnolol inhibits NO...

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Bibliographic Details
Main Authors: Ching-Shu Lai, You-Syuan Lai, Daih-Huang Kuo, Chih-Hsiung Wu, Chi-Tang Ho, Min-Hsiung Pan
Format: Article
Language:English
Published: Elsevier 2011-07-01
Series:Journal of Functional Foods
Subjects:
Magnolol
Inducible NO synthase (iNOS)
NF-κB
RAW 264.7 monocyte/macrophages
Lipopolysaccharide (LPS)
Mitogen-activated protein kinase (MAPK)
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464611000491

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