Lymphocytopenia may be a new indicator for infected obstructed kidneys secondary to urinary stone disease

Objective: Infected obstructed kidney (IOK) is a urological emergency. We wanted to look at the role of serum inflammatory markers in these patients. Materials and Methods: Patients with IOK requiring percutaneous nephrostomy (PCN) at our university hospital were identified, and data were collected...

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Bibliographic Details
Main Authors: Ahmed Ali, Liam Farell, Bhaskar K Somani
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Urology Annals
Subjects:
Online Access:http://www.urologyannals.com/article.asp?issn=0974-7796;year=2015;volume=7;issue=4;spage=475;epage=477;aulast=Ali
Description
Summary:Objective: Infected obstructed kidney (IOK) is a urological emergency. We wanted to look at the role of serum inflammatory markers in these patients. Materials and Methods: Patients with IOK requiring percutaneous nephrostomy (PCN) at our university hospital were identified, and data were collected on lymphocyte count, C-reactive protein (CRP) and microbiology results. Results: Thirty-nine patients had PCN for IOK. Lymphocytopenia was seen in two-thirds of these patients. Severe lymphocytopenia was associated with a significant rise in CRP in all cases and following PCN, lymphocytopenia improved in the majority of cases. Conclusions: Lymphocytopenia seems to be associated with the severity of infection and could be a surrogate marker on its own or in conjunction with CRP for initial diagnosis and monitoring response to treatment in patients with IOKs.
ISSN:0974-7796
0974-7834