Lymphocytopenia may be a new indicator for infected obstructed kidneys secondary to urinary stone disease
Objective: Infected obstructed kidney (IOK) is a urological emergency. We wanted to look at the role of serum inflammatory markers in these patients. Materials and Methods: Patients with IOK requiring percutaneous nephrostomy (PCN) at our university hospital were identified, and data were collected...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2015-01-01
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| Series: | Urology Annals |
| Subjects: | |
| Online Access: | http://www.urologyannals.com/article.asp?issn=0974-7796;year=2015;volume=7;issue=4;spage=475;epage=477;aulast=Ali |
| _version_ | 1819090918819495936 |
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| author | Ahmed Ali Liam Farell Bhaskar K Somani |
| author_facet | Ahmed Ali Liam Farell Bhaskar K Somani |
| author_sort | Ahmed Ali |
| collection | DOAJ |
| description | Objective: Infected obstructed kidney (IOK) is a urological emergency. We wanted to look at the role of serum inflammatory markers in these patients.
Materials and Methods: Patients with IOK requiring percutaneous nephrostomy (PCN) at our university hospital were identified, and data were collected on lymphocyte count, C-reactive protein (CRP) and microbiology results.
Results: Thirty-nine patients had PCN for IOK. Lymphocytopenia was seen in two-thirds of these patients. Severe lymphocytopenia was associated with a significant rise in CRP in all cases and following PCN, lymphocytopenia improved in the majority of cases.
Conclusions: Lymphocytopenia seems to be associated with the severity of infection and could be a surrogate marker on its own or in conjunction with CRP for initial diagnosis and monitoring response to treatment in patients with IOKs. |
| first_indexed | 2024-12-21T22:31:28Z |
| format | Article |
| id | doaj.art-4c80046884684e5695bf8dcb06d8157c |
| institution | Directory Open Access Journal |
| issn | 0974-7796 0974-7834 |
| language | English |
| last_indexed | 2024-12-21T22:31:28Z |
| publishDate | 2015-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Urology Annals |
| spelling | doaj.art-4c80046884684e5695bf8dcb06d8157c2022-12-21T18:48:05ZengWolters Kluwer Medknow PublicationsUrology Annals0974-77960974-78342015-01-017447547710.4103/0974-7796.157965Lymphocytopenia may be a new indicator for infected obstructed kidneys secondary to urinary stone diseaseAhmed AliLiam FarellBhaskar K SomaniObjective: Infected obstructed kidney (IOK) is a urological emergency. We wanted to look at the role of serum inflammatory markers in these patients. Materials and Methods: Patients with IOK requiring percutaneous nephrostomy (PCN) at our university hospital were identified, and data were collected on lymphocyte count, C-reactive protein (CRP) and microbiology results. Results: Thirty-nine patients had PCN for IOK. Lymphocytopenia was seen in two-thirds of these patients. Severe lymphocytopenia was associated with a significant rise in CRP in all cases and following PCN, lymphocytopenia improved in the majority of cases. Conclusions: Lymphocytopenia seems to be associated with the severity of infection and could be a surrogate marker on its own or in conjunction with CRP for initial diagnosis and monitoring response to treatment in patients with IOKs.http://www.urologyannals.com/article.asp?issn=0974-7796;year=2015;volume=7;issue=4;spage=475;epage=477;aulast=AliCalculiinfected obstructed kidneylymphocytopenianephrostomy |
| spellingShingle | Ahmed Ali Liam Farell Bhaskar K Somani Lymphocytopenia may be a new indicator for infected obstructed kidneys secondary to urinary stone disease Urology Annals Calculi infected obstructed kidney lymphocytopenia nephrostomy |
| title | Lymphocytopenia may be a new indicator for infected obstructed kidneys secondary to urinary stone disease |
| title_full | Lymphocytopenia may be a new indicator for infected obstructed kidneys secondary to urinary stone disease |
| title_fullStr | Lymphocytopenia may be a new indicator for infected obstructed kidneys secondary to urinary stone disease |
| title_full_unstemmed | Lymphocytopenia may be a new indicator for infected obstructed kidneys secondary to urinary stone disease |
| title_short | Lymphocytopenia may be a new indicator for infected obstructed kidneys secondary to urinary stone disease |
| title_sort | lymphocytopenia may be a new indicator for infected obstructed kidneys secondary to urinary stone disease |
| topic | Calculi infected obstructed kidney lymphocytopenia nephrostomy |
| url | http://www.urologyannals.com/article.asp?issn=0974-7796;year=2015;volume=7;issue=4;spage=475;epage=477;aulast=Ali |
| work_keys_str_mv | AT ahmedali lymphocytopeniamaybeanewindicatorforinfectedobstructedkidneyssecondarytourinarystonedisease AT liamfarell lymphocytopeniamaybeanewindicatorforinfectedobstructedkidneyssecondarytourinarystonedisease AT bhaskarksomani lymphocytopeniamaybeanewindicatorforinfectedobstructedkidneyssecondarytourinarystonedisease |