IGFBP-3 inhibits cytokine-induced insulin resistance and early manifestations of atherosclerosis.

IGFBP-3 inhibits cytokine-induced insulin resistance and early manifestations of atherosclerosis.

Metabolic syndrome is associated with visceral obesity, insulin resistance and an increased risk of cardiovascular diseases. Visceral fat tissue primarily consists of adipocytes that secrete cytokines leading to a state of systemic inflammation in obese conditions. One of the IGF-independent functio...

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Bibliographic Details
Main Authors: Lathika Mohanraj, Ho-Seong Kim, Wei Li, Qing Cai, Ki Eun Kim, Hye-Jung Shin, Yong-Jae Lee, Woo Jung Lee, Jung Hyun Kim, Youngman Oh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3557269?pdf=render

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