The Adipokine Chemerin Induces Apoptosis in Cardiomyocytes

The Adipokine Chemerin Induces Apoptosis in Cardiomyocytes

Background: The adipokine chemerin has been associated with cardiovascular disease. We investigated the effects of chemerin on viability and intracellular signalling in murine cardiomyocytes, and the effects of insulin and TNF-α on cardiomyocyte chemerin production. Methods: Hoechst dye vital staini...

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Bibliographic Details
Main Authors: Diego Rodríguez-Penas, Sandra Feijóo-Bandín, Vanessa García-Rúa, Ana Mosquera-Leal, Darío Durán, Alfonso Varela, Manuel Portolés, Esther Roselló-Lletí, Miguel Rivera, Carlos Diéguez, Oreste Gualillo, José Ramón González-Juanatey, Francisca Lago
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-08-01
Series:Cellular Physiology and Biochemistry
Subjects:
Cardiomyocyte
TNF-α
Insulin resistance
AKT
HL-1
Apoptosis
Chemerin
Online Access:http://www.karger.com/Article/FullText/430343

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