Phytochemical screening and antioxidant profiling of Sumatran wild mangoes (Mangifera spp.): a potential source for medicine antidegenerative effects [version 3; peer review: 2 approved]
Background: New findings on the potential of wild mangoes from the island of Sumatra as a source of antioxidant helps their conservation effort as it introduces their useful compounds to the public. This study aims to analyze the antioxidant profile and quantification of gallic acid and quercetin co...
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| Format: | Article |
| Language: | English |
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F1000 Research Ltd
2020-06-01
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| Series: | F1000Research |
| Online Access: | https://f1000research.com/articles/9-220/v3 |
| _version_ | 1818500447935135744 |
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| author | Fitmawati Fitmawati Esi Resida Sri Nur Kholifah Rodesia Mustika Roza Muhammad Almurdani Emrizal Emrizal |
| author_facet | Fitmawati Fitmawati Esi Resida Sri Nur Kholifah Rodesia Mustika Roza Muhammad Almurdani Emrizal Emrizal |
| author_sort | Fitmawati Fitmawati |
| collection | DOAJ |
| description | Background: New findings on the potential of wild mangoes from the island of Sumatra as a source of antioxidant helps their conservation effort as it introduces their useful compounds to the public. This study aims to analyze the antioxidant profile and quantification of gallic acid and quercetin content from leaves and bark of Sumatran wild mangoes. Exploration and analysis of phytochemical constituents from 11 Sumatran wild mangoes was performed. Methods: Antioxidant activity of wild mangoes was analysed with 1,1- diphenyl-2-picryl hydroxyl (DPPH), and determination of quercetin and gallic acid content was performed by high performance liquid chromatography (HPLC) method. Total flavonoid and phenolic analysis was also performed. Curve fitting analysis used a linear regression approach. Results: The highest level of antioxidant activity, phenolic compound and flavonoid compound was found in the leaves and bark of Mangifera sp1. (MBS), the bark of M. foetida 3 (var. batu) and leaves of M. torquenda, and the bark and leaves of M. sumatrana, respectively. The content of gallic acid in leaves ranged from 5.23-35.48 mg/g dry weight. Quercetin content of wild mangoes leaves ranged from 0.76 to 1.16 mg/g dry weight with the lowest value in M. foetida 2 (var. manis) and the highest in M. laurina. Conclusion: The results obtained are expected to be useful in supporting the development of drugs that have antidegenerative effects. |
| first_indexed | 2024-12-10T20:42:52Z |
| format | Article |
| id | doaj.art-4c84914692ac4402aebf0abde94eb02c |
| institution | Directory Open Access Journal |
| issn | 2046-1402 |
| language | English |
| last_indexed | 2024-12-10T20:42:52Z |
| publishDate | 2020-06-01 |
| publisher | F1000 Research Ltd |
| record_format | Article |
| series | F1000Research |
| spelling | doaj.art-4c84914692ac4402aebf0abde94eb02c2022-12-22T01:34:18ZengF1000 Research LtdF1000Research2046-14022020-06-01910.12688/f1000research.22380.327684Phytochemical screening and antioxidant profiling of Sumatran wild mangoes (Mangifera spp.): a potential source for medicine antidegenerative effects [version 3; peer review: 2 approved]Fitmawati Fitmawati0Esi Resida1Sri Nur Kholifah2Rodesia Mustika Roza3Muhammad Almurdani4Emrizal Emrizal5Department of Biology, Faculty of Mathematics and Natural Sciences, Universitas Riau, Pekanbaru, Riau, 28293, IndonesiaDepartment of Biology, Faculty of Mathematics and Natural Sciences, Universitas Riau, Pekanbaru, Riau, 28293, IndonesiaDepartment of Biology, Faculty of Mathematics and Natural Sciences, Universitas Riau, Pekanbaru, Riau, 28293, IndonesiaDepartment of Biology, Faculty of Mathematics and Natural Sciences, Universitas Riau, Pekanbaru, Riau, 28293, IndonesiaDepartment of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Riau, Pekanbaru, Riau, 28293, IndonesiaSchool of Riau Pharmacy, Pekanbaru, Riau, 28293, IndonesiaBackground: New findings on the potential of wild mangoes from the island of Sumatra as a source of antioxidant helps their conservation effort as it introduces their useful compounds to the public. This study aims to analyze the antioxidant profile and quantification of gallic acid and quercetin content from leaves and bark of Sumatran wild mangoes. Exploration and analysis of phytochemical constituents from 11 Sumatran wild mangoes was performed. Methods: Antioxidant activity of wild mangoes was analysed with 1,1- diphenyl-2-picryl hydroxyl (DPPH), and determination of quercetin and gallic acid content was performed by high performance liquid chromatography (HPLC) method. Total flavonoid and phenolic analysis was also performed. Curve fitting analysis used a linear regression approach. Results: The highest level of antioxidant activity, phenolic compound and flavonoid compound was found in the leaves and bark of Mangifera sp1. (MBS), the bark of M. foetida 3 (var. batu) and leaves of M. torquenda, and the bark and leaves of M. sumatrana, respectively. The content of gallic acid in leaves ranged from 5.23-35.48 mg/g dry weight. Quercetin content of wild mangoes leaves ranged from 0.76 to 1.16 mg/g dry weight with the lowest value in M. foetida 2 (var. manis) and the highest in M. laurina. Conclusion: The results obtained are expected to be useful in supporting the development of drugs that have antidegenerative effects.https://f1000research.com/articles/9-220/v3 |
| spellingShingle | Fitmawati Fitmawati Esi Resida Sri Nur Kholifah Rodesia Mustika Roza Muhammad Almurdani Emrizal Emrizal Phytochemical screening and antioxidant profiling of Sumatran wild mangoes (Mangifera spp.): a potential source for medicine antidegenerative effects [version 3; peer review: 2 approved] F1000Research |
| title | Phytochemical screening and antioxidant profiling of Sumatran wild mangoes (Mangifera spp.): a potential source for medicine antidegenerative effects [version 3; peer review: 2 approved] |
| title_full | Phytochemical screening and antioxidant profiling of Sumatran wild mangoes (Mangifera spp.): a potential source for medicine antidegenerative effects [version 3; peer review: 2 approved] |
| title_fullStr | Phytochemical screening and antioxidant profiling of Sumatran wild mangoes (Mangifera spp.): a potential source for medicine antidegenerative effects [version 3; peer review: 2 approved] |
| title_full_unstemmed | Phytochemical screening and antioxidant profiling of Sumatran wild mangoes (Mangifera spp.): a potential source for medicine antidegenerative effects [version 3; peer review: 2 approved] |
| title_short | Phytochemical screening and antioxidant profiling of Sumatran wild mangoes (Mangifera spp.): a potential source for medicine antidegenerative effects [version 3; peer review: 2 approved] |
| title_sort | phytochemical screening and antioxidant profiling of sumatran wild mangoes mangifera spp a potential source for medicine antidegenerative effects version 3 peer review 2 approved |
| url | https://f1000research.com/articles/9-220/v3 |
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