A fourth dose of the inactivated SARS-CoV-2 vaccine redistributes humoral immunity to the N-terminal domain
Despite the availability of booster doses against SARS-CoV-2, variants of concern are capable of escaping immune responses established by vaccination or natural infection. In this work, the authors detail the immune responses elicited in a cohort of healthcare workers, receiving a fourth dose of ina...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-11-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-34633-7 |
| _version_ | 1828130652132737024 |
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| author | Ji Wang Caiguangxi Deng Ming Liu Yihao Liu Liubing Li Zhangping Huang Liru Shang Juan Jiang Yongyong Li Ruohui Mo Hui Zhang Min Liu Sui Peng Haipeng Xiao |
| author_facet | Ji Wang Caiguangxi Deng Ming Liu Yihao Liu Liubing Li Zhangping Huang Liru Shang Juan Jiang Yongyong Li Ruohui Mo Hui Zhang Min Liu Sui Peng Haipeng Xiao |
| author_sort | Ji Wang |
| collection | DOAJ |
| description | Despite the availability of booster doses against SARS-CoV-2, variants of concern are capable of escaping immune responses established by vaccination or natural infection. In this work, the authors detail the immune responses elicited in a cohort of healthcare workers, receiving a fourth dose of inactivated vaccine. |
| first_indexed | 2024-04-11T16:35:48Z |
| format | Article |
| id | doaj.art-4c88e33b921047e8a73e8143a1250573 |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-04-11T16:35:48Z |
| publishDate | 2022-11-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-4c88e33b921047e8a73e8143a12505732022-12-22T04:13:51ZengNature PortfolioNature Communications2041-17232022-11-0113111110.1038/s41467-022-34633-7A fourth dose of the inactivated SARS-CoV-2 vaccine redistributes humoral immunity to the N-terminal domainJi Wang0Caiguangxi Deng1Ming Liu2Yihao Liu3Liubing Li4Zhangping Huang5Liru Shang6Juan Jiang7Yongyong Li8Ruohui Mo9Hui Zhang10Min Liu11Sui Peng12Haipeng Xiao13Department of Endocrinology, The First Affiliated Hospital, Sun Yat-sen UniversityInstitute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen UniversityInstitute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen UniversityClinical Trials Unit, The First Affiliated Hospital, Sun Yat-sen UniversityDepartment of Laboratory Medicine, The First Affiliated Hospital, Sun Yat-sen UniversityInstitute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen UniversityInstitute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen UniversityInstitute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen UniversityInstitute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen UniversityClinical Trials Unit, The First Affiliated Hospital, Sun Yat-sen UniversityInstitute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen UniversityDepartment of Laboratory Medicine, The First Affiliated Hospital, Sun Yat-sen UniversityInstitute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen UniversityDepartment of Endocrinology, The First Affiliated Hospital, Sun Yat-sen UniversityDespite the availability of booster doses against SARS-CoV-2, variants of concern are capable of escaping immune responses established by vaccination or natural infection. In this work, the authors detail the immune responses elicited in a cohort of healthcare workers, receiving a fourth dose of inactivated vaccine.https://doi.org/10.1038/s41467-022-34633-7 |
| spellingShingle | Ji Wang Caiguangxi Deng Ming Liu Yihao Liu Liubing Li Zhangping Huang Liru Shang Juan Jiang Yongyong Li Ruohui Mo Hui Zhang Min Liu Sui Peng Haipeng Xiao A fourth dose of the inactivated SARS-CoV-2 vaccine redistributes humoral immunity to the N-terminal domain Nature Communications |
| title | A fourth dose of the inactivated SARS-CoV-2 vaccine redistributes humoral immunity to the N-terminal domain |
| title_full | A fourth dose of the inactivated SARS-CoV-2 vaccine redistributes humoral immunity to the N-terminal domain |
| title_fullStr | A fourth dose of the inactivated SARS-CoV-2 vaccine redistributes humoral immunity to the N-terminal domain |
| title_full_unstemmed | A fourth dose of the inactivated SARS-CoV-2 vaccine redistributes humoral immunity to the N-terminal domain |
| title_short | A fourth dose of the inactivated SARS-CoV-2 vaccine redistributes humoral immunity to the N-terminal domain |
| title_sort | fourth dose of the inactivated sars cov 2 vaccine redistributes humoral immunity to the n terminal domain |
| url | https://doi.org/10.1038/s41467-022-34633-7 |
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