Enhanced Proapoptotic Effects of Water Dispersed Complexes of 4-Thiazolidinone-Based Chemotherapeutics with a PEG-Containing Polymeric Nanocarrier

Enhanced Proapoptotic Effects of Water Dispersed Complexes of 4-Thiazolidinone-Based Chemotherapeutics with a PEG-Containing Polymeric Nanocarrier

Abstract Aim To study whether water formulation of the complex of 4-thiazolidinone derivatives with a PEG-containing polymeric nanocarrier enhances their pro-apoptotic action towards rat glioma C6 cells. Methods Mechanisms of antineoplastic effects of 4-thiazolidinone derivatives were investigated i...

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Bibliographic Details
Main Authors: L. Kobylinska, I. Ivasechko, N. Skorokhyd, R. Panchuk, A. Riabtseva, N. Mitina, A. Zaichenko, R. Lesyk, B. Zimenkovsky, R. Stoika, S. G. Vari
Format: Article
Language:English
Published: SpringerOpen 2019-04-01
Series:Nanoscale Research Letters
Subjects:
4-thiazolidinones
Polyethylene glycol
Polymeric nanocarrier
Apoptosis
Rat glioma C6 cells
Online Access:http://link.springer.com/article/10.1186/s11671-019-2945-7

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