Efficacy of Immunization against a Novel Synthetic 13-Amino Acid Betaglycan-Binding Peptide Sequence of Inhibin α Subunit on Promoting Fertility in Female Rats
Inhibins suppress the FSH production in pituitary gonadotrope cells by robustly antagonizing activin signaling by competitively binding to activin type II receptors (ACTR II). The binding of inhibin A to ACTR II requires the presence of its co-receptor, namely, betaglycan. In humans, the critical bi...
Main Authors: | Xingfa Han, Xue Xia, Weihao Chen, Fengyan Meng, Xiaohan Cao, Guixian Bu, Tian Gan, Xiaogang Du, Qiuxia Liang, Xianyin Zeng |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-04-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/24/8/6914 |
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