Efficacy of Immunization against a Novel Synthetic 13-Amino Acid Betaglycan-Binding Peptide Sequence of Inhibin α Subunit on Promoting Fertility in Female Rats

Efficacy of Immunization against a Novel Synthetic 13-Amino Acid Betaglycan-Binding Peptide Sequence of Inhibin α Subunit on Promoting Fertility in Female Rats

Inhibins suppress the FSH production in pituitary gonadotrope cells by robustly antagonizing activin signaling by competitively binding to activin type II receptors (ACTR II). The binding of inhibin A to ACTR II requires the presence of its co-receptor, namely, betaglycan. In humans, the critical bi...

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Bibliographic Details
Main Authors: Xingfa Han, Xue Xia, Weihao Chen, Fengyan Meng, Xiaohan Cao, Guixian Bu, Tian Gan, Xiaogang Du, Qiuxia Liang, Xianyin Zeng
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
inhibin
vaccine
folliculogenesis
ovulation
fertility
rat
Online Access:https://www.mdpi.com/1422-0067/24/8/6914

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