Women With Congenital Hypofibrinogenemia/Afibrinogenemia: From Birth to Death
Congenital fibrinogen disorders are a group of most frequent rare coagulation disorder, characterized by deficiency and/or defects in the fibrinogen molecule. Quantitative disorders include hypofibrinogenemia and afibrinogenemia. Due to their specific physiological characteristics, female patients t...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2020-03-01
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| Series: | Clinical and Applied Thrombosis/Hemostasis |
| Online Access: | https://doi.org/10.1177/1076029620912819 |
| _version_ | 1818502339002105856 |
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| author | Yan Zhang MD Xiaohang Zuo MD Yue Teng PhD, MD |
| author_facet | Yan Zhang MD Xiaohang Zuo MD Yue Teng PhD, MD |
| author_sort | Yan Zhang MD |
| collection | DOAJ |
| description | Congenital fibrinogen disorders are a group of most frequent rare coagulation disorder, characterized by deficiency and/or defects in the fibrinogen molecule. Quantitative disorders include hypofibrinogenemia and afibrinogenemia. Due to their specific physiological characteristics, female patients tend to have congenital hypofibrinogenemia/afibrinogenemia, such as spontaneous recurrent abortion, menorrhagia, infertility, antepartum and postpartum hemorrhage, and so on. Current studies of congenital hypofibrinogenemia/afibrinogenemia mainly focus on different types of fibrinogen mutations, etiology/pathogenesis, and some rare case reports of the diseases. So far, there is no study available to systematically review the specific features of female patients with congenital bleeding disorders. This review aims to deal with hematological, gynecologic and obstetric issues, and relevant clinical management of congenital hypofibrinogenemia/afibrinogenemia at different life stages of female patients. We believe this review provides valuable reference for clinicians in the field of hematology, obstetrics, as well as gynecology. |
| first_indexed | 2024-12-10T21:08:55Z |
| format | Article |
| id | doaj.art-4c90b1e5988440c2970f01071ad02062 |
| institution | Directory Open Access Journal |
| issn | 1938-2723 |
| language | English |
| last_indexed | 2024-12-10T21:08:55Z |
| publishDate | 2020-03-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Clinical and Applied Thrombosis/Hemostasis |
| spelling | doaj.art-4c90b1e5988440c2970f01071ad020622022-12-22T01:33:33ZengSAGE PublishingClinical and Applied Thrombosis/Hemostasis1938-27232020-03-012610.1177/1076029620912819Women With Congenital Hypofibrinogenemia/Afibrinogenemia: From Birth to DeathYan Zhang MD0Xiaohang Zuo MD1Yue Teng PhD, MD2 Nursing Department, Baoji Maternal and Child Health Hospital, Baoji, China No. 986 Air Force Hospital of PLA, Xi’an, China School of Life Science and Technology, Xi’an Jiaotong University, Xi’an, ChinaCongenital fibrinogen disorders are a group of most frequent rare coagulation disorder, characterized by deficiency and/or defects in the fibrinogen molecule. Quantitative disorders include hypofibrinogenemia and afibrinogenemia. Due to their specific physiological characteristics, female patients tend to have congenital hypofibrinogenemia/afibrinogenemia, such as spontaneous recurrent abortion, menorrhagia, infertility, antepartum and postpartum hemorrhage, and so on. Current studies of congenital hypofibrinogenemia/afibrinogenemia mainly focus on different types of fibrinogen mutations, etiology/pathogenesis, and some rare case reports of the diseases. So far, there is no study available to systematically review the specific features of female patients with congenital bleeding disorders. This review aims to deal with hematological, gynecologic and obstetric issues, and relevant clinical management of congenital hypofibrinogenemia/afibrinogenemia at different life stages of female patients. We believe this review provides valuable reference for clinicians in the field of hematology, obstetrics, as well as gynecology.https://doi.org/10.1177/1076029620912819 |
| spellingShingle | Yan Zhang MD Xiaohang Zuo MD Yue Teng PhD, MD Women With Congenital Hypofibrinogenemia/Afibrinogenemia: From Birth to Death Clinical and Applied Thrombosis/Hemostasis |
| title | Women With Congenital Hypofibrinogenemia/Afibrinogenemia: From Birth to Death |
| title_full | Women With Congenital Hypofibrinogenemia/Afibrinogenemia: From Birth to Death |
| title_fullStr | Women With Congenital Hypofibrinogenemia/Afibrinogenemia: From Birth to Death |
| title_full_unstemmed | Women With Congenital Hypofibrinogenemia/Afibrinogenemia: From Birth to Death |
| title_short | Women With Congenital Hypofibrinogenemia/Afibrinogenemia: From Birth to Death |
| title_sort | women with congenital hypofibrinogenemia afibrinogenemia from birth to death |
| url | https://doi.org/10.1177/1076029620912819 |
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