Primary Myeloid Sarcoma of Ovary: A Case Report and Review of the Literature
Myeloid sarcoma (granulocytic sarcoma or chloroma) is a tumor formed by myeloid precursor cells in any localization other than the bone marrow. It can occur without underlying acute myeloid leukemia (AML) or other myeloid neoplasms. Herein, we present a forty-two-year-old female patient who underwen...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Federation of Turkish Pathology Societies
2021-09-01
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| Series: | Türk Patoloji Dergisi |
| Subjects: | |
| Online Access: |
http://www.turkjpath.org/pdf.php3?id=1953
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| _version_ | 1797907081475391488 |
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| author | Sevda AKYOL Fatma OZ ATALAY |
| author_facet | Sevda AKYOL Fatma OZ ATALAY |
| author_sort | Sevda AKYOL |
| collection | DOAJ |
| description | Myeloid sarcoma (granulocytic sarcoma or chloroma) is a tumor formed by myeloid precursor cells in any localization other than the bone marrow. It can occur without underlying acute myeloid leukemia (AML) or other myeloid neoplasms. Herein, we present a forty-two-year-old female patient who underwent surgery because of a left adnexal mass. Microscopic examination of the specimen revealed cord-like arrangement of the tumor cells with a diffuse growth of small blue cells effacing the ovarian stroma. Adult granulosa cell tumor was in the differential given the scanty cytoplasm of the tumor and in fact was the diagnosis of the referring institution. Further microscopic evaluation with immunohistochemical analysis at our institution revised the diagnosis to myeloid sarcoma. Myeloid sarcoma is a difficult tumor to diagnose due to its rarity, especially in the absence of a history of leukemia, and correct tissue diagnosis is essential for its treatment. |
| first_indexed | 2024-04-10T10:30:49Z |
| format | Article |
| id | doaj.art-4c913abd3ca64c3e84aa136a20b44517 |
| institution | Directory Open Access Journal |
| issn | 1018-5615 1309-5730 |
| language | English |
| last_indexed | 2024-04-10T10:30:49Z |
| publishDate | 2021-09-01 |
| publisher | Federation of Turkish Pathology Societies |
| record_format | Article |
| series | Türk Patoloji Dergisi |
| spelling | doaj.art-4c913abd3ca64c3e84aa136a20b445172023-02-15T16:21:08ZengFederation of Turkish Pathology SocietiesTürk Patoloji Dergisi1018-56151309-57302021-09-0137324925310.5146/tjpath.2020.01517Primary Myeloid Sarcoma of Ovary: A Case Report and Review of the LiteratureSevda AKYOLFatma OZ ATALAYMyeloid sarcoma (granulocytic sarcoma or chloroma) is a tumor formed by myeloid precursor cells in any localization other than the bone marrow. It can occur without underlying acute myeloid leukemia (AML) or other myeloid neoplasms. Herein, we present a forty-two-year-old female patient who underwent surgery because of a left adnexal mass. Microscopic examination of the specimen revealed cord-like arrangement of the tumor cells with a diffuse growth of small blue cells effacing the ovarian stroma. Adult granulosa cell tumor was in the differential given the scanty cytoplasm of the tumor and in fact was the diagnosis of the referring institution. Further microscopic evaluation with immunohistochemical analysis at our institution revised the diagnosis to myeloid sarcoma. Myeloid sarcoma is a difficult tumor to diagnose due to its rarity, especially in the absence of a history of leukemia, and correct tissue diagnosis is essential for its treatment. http://www.turkjpath.org/pdf.php3?id=1953 myeloid sarcomaovaryfemale genital neoplasms |
| spellingShingle | Sevda AKYOL Fatma OZ ATALAY Primary Myeloid Sarcoma of Ovary: A Case Report and Review of the Literature Türk Patoloji Dergisi myeloid sarcoma ovary female genital neoplasms |
| title | Primary Myeloid Sarcoma of Ovary: A Case Report and Review of the Literature |
| title_full | Primary Myeloid Sarcoma of Ovary: A Case Report and Review of the Literature |
| title_fullStr | Primary Myeloid Sarcoma of Ovary: A Case Report and Review of the Literature |
| title_full_unstemmed | Primary Myeloid Sarcoma of Ovary: A Case Report and Review of the Literature |
| title_short | Primary Myeloid Sarcoma of Ovary: A Case Report and Review of the Literature |
| title_sort | primary myeloid sarcoma of ovary a case report and review of the literature |
| topic | myeloid sarcoma ovary female genital neoplasms |
| url |
http://www.turkjpath.org/pdf.php3?id=1953
|
| work_keys_str_mv | AT sevdaakyol primarymyeloidsarcomaofovaryacasereportandreviewoftheliterature AT fatmaozatalay primarymyeloidsarcomaofovaryacasereportandreviewoftheliterature |